purpose: To evaluate the efficacy and safety of flexible ureteroscopy
and laser lithotripsy(FURSL) for treatment of the upper urinary tract
calculi. Methods: We retrospectively analyzed 784 patients who underwent
FURSL between January 2015 to October 2020 in our unit. The operative
parameters, postoperative functional outcomes and complications were
recorded respectively. Rusults: All patients underwent successful
operation. The mean operative time was 46.9±15.8min. The average
postoperative hospital stay was 1.2±1.1 days. The postoperative serum
creatinine and hemoglobin were 76.2±10.2umol/L and 133.6±5.1g/L, which
compared to preoperative, there were no sigificant statistical
difference. Among 784 patients, 746 patients were followed up and 38
patients were lost. 700(93.8%) cases met the stone removal critetia and
46 cases(6.2%) did not meet the stone removal criteria for other
treatments, such as extracorporeal shock wave lithotripsy, ureteroscopy
and observed regularly. The stone free rate(SFR) is 92.5% after 1-3
months and SFR of middle and upper calyceal calculi was higher than that
of lower calyceal calculi significantly. The most common complications
were fever(58/784,7.4%),gross hematuria(540/784,68.88%) and
lpsilateral low back pain(47/784,5.99). The incidence rate of serious
complication was 1.28%(10/784), including 5 cases of septic shock and 5
cases of subcapsular hematoma, which were cured after active treatment.
Conclusion: FURSL is a reliable treatment for small and medium calculi
patients of upper urinary tract. The curative effect of stone removal is
clear,the complications are few and the safety is high. However there
are certain limitation to the efficacy in the treatment of large stone
and lower calyceal calculi.