Prebiotics for people with cystic fibrosis

Abstract

To evaluate the benefits and harms of prebiotics for improving health outcomes in children and adults with CF.

In vitro screening of the impact of dietary prebiotic components, probiotic strains, and their symbiotic combinations on colonic microbiota in children with cystic fibrosis

“…The relevance of the study is that new evidence on the role of different probiotics, prebiotics and their synbiotic combinations on CF gut dysbiosis has been generated, in an emerging study field where scarce or null knowledge is available. 50,51 The new findings are to be interpreted with caution as the study was carried out in an in vitro setting. Besides, we acknowledge the limitation of the colonic fermentation model, which despite being adapted to the CF intestinal conditions, might not be fully representative of a CF colon.…”