Precalcaneal Congenital Fibrolipomatous Hamartoma

Rubio-Flores, C.; González, O. López-Barrantes; Garrido-Gutiérrez, C.; Diaz‐Díaz, R.M.

doi:10.1016/j.adengl.2012.08.019

Cited by 3 publications

(9 citation statements)

References 7 publications

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“…Histopathology shows mature adipose tissue surrounded by collagen fibers of different thickness . An increased number of blood vessels has also been reported but without any perivascular alterations .…”

Section: Discussionmentioning

confidence: 88%

“…Incomplete regression of fibrolipomatous fetal tissue in the area of the heel is one proposed hypothesis. However, lack of fetal tissue on histology and absence of increased incidence of PCFH in preterm infants refutes this hypothesis . Congenital alteration of fibroconnective trabecular network of adipose tissue has been suggested .…”

Section: Discussionmentioning

confidence: 99%

“…However, lack of fetal tissue on histology and absence of increased incidence of PCFH in preterm infants refutes this hypothesis . Congenital alteration of fibroconnective trabecular network of adipose tissue has been suggested . PCFH has been shown to have an X‐linked or mitochondrial inheritance pattern .…”

Section: Discussionmentioning

confidence: 99%

“…PCFH has been shown to have an X‐linked or mitochondrial inheritance pattern . Most of the cases of PCFH are sporadic although familial cases have also been described . Single case reports have highlighted the association of PCFH with Gardner syndrome and tuberous sclerosis .…”

Section: Discussionmentioning

confidence: 99%

“…Differential diagnoses of PCFH include piezogenic papules, juvenile fibromatosis, focal dermal hypoplasia, nevus lipomatosus, and lipoma . Piezogenic papules are herniations of fat through dermis and are seen in adults.…”

Section: Discussionmentioning

confidence: 99%

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Precalcaneal congenital fibrolipomatous hamartoma: Rare or under‐reported?

et al. 2019

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Precalcaneal congenital fibrolipomatous hamartoma (PCFH) is a benign under-reported condition of infancy characterized by the presence of soft nodules on precalcaneal plantar surface of the heel. These lesions are usually bilateral solitary and asymptomatic. We present a 2-monthold infant with solitary skin-colored nodules present on precalcaneal plantar aspect of bilateral heels. K E Y W O R D Scongenital piezogenic-like papules, fibrolipomatous hamartoma, pedal papules, precalcaneal congenital fibrolipomatous hamartoma 1 | INTRODUCTION Precalcaneal congenital fibrolipomatous hamartoma (PCFH) is a benign condition that has been referred by disparate nomenclature such as congenital piezogenic-like papules, infantile pedal papules, congenital adipose plantar nodules, and plantar nodules. 1-3 There is apparent lack of published reports in English literature that may be because either the entity is under-diagnosed or misdiagnosed. PCFH is characterized by soft asymptomatic nodules on the plantar aspect of foot. The condition generally presents within first few months of life but can be present at birth. 3 The condition is often bilateral, although unilateral involvement has also been reported. 4,5 The nodules may grow proportionately with the child's growth. 4 No systemic association has been identified so far. We present a case of 2-month old girl infant with skin-colored nodules on precalcaneal aspect of bilateral heel. | CASE REPORTA 2 month-old girl apparently healthy infant, born out of a nonconsanguineous marriage and first in birth order, was brought by her parents for consultation regarding nodular lesions on the plantar aspect of bilateral heel. The infant was born at full term by normal vaginal delivery. The lesions were present since birth and have not changed in appearance since then. On examination, a solitary, skin-colored soft, non-tender nodular-lesion was present on the medial aspect of precalcaneal region of both heels. The individual lesion was approximately 2 × 2 cm in size, poorly circumscribed and freely mobile, with normal overlying skin (Figure 1). The rest of the mucocutaneous and systemic examination was normal. Ultrasound examination revealed an ill-defined slightly hyperechoeic lesion with no increase in vascularity. A skin biopsy was sent from the left heel lesion. The hematoxylin and eosin stained section showed presence of mature adipose tissue enveloped with collagenous fibrous sheaths without any evidence of inflammation seen encircling the appendages (Figure 2A,B). Based on the clinical presentation, typical location and histology, a diagnosis of PCFH was made. The parents were counseled regarding the benign nature of the lesion.

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Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Precalcaneal congenital fibrolipomatous hamartoma: Rare or under‐reported?

et al. 2019

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Cutaneous fibrolipomatous hamartoma: Report of 2 cases with retrocalcaneal location

Bandera

Saylor

Beato

et al. 2018

Pediatric Dermatology

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Precalcaneal congenital fibrolipomatous hamartoma is an underreported benign entity that has been described in the literature under different names. We present two cases of unilateral fibrolipomatous hamartoma (FLH) appearing in a unique location: on the posterior aspect of the foot overlying the heel. We propose the term "FLH of the skin" as a more inclusive and less confusing term for this condition, thus allowing distinction with FLH arising from neural tissue. High-frequency ultrasonography appears to be a useful diagnostic tool that may avoid unnecessary biopsies for this condition.

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A plantar subcutaneous nodule in a healthy infant

Borg,

Micallef,

Betts

et al. 2024

Pediatric Dermatology

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An 8-month-old boy presented with a lesion on the plantar aspect of his left hindfoot. The lesion was completely asymptomatic and, according to the child's parents, had been present since birth but grew proportionally to the infant. Physical examination revealed a soft, non-tender, subcutaneous nodule approximately 1 cm in diameter anterior to the heel with normal overlying skin (Figure 1). A full skin examination showed no other abnormalities elsewhere. The patient had an ultrasound scan of the lesion followed by a diagnostic punch biopsy. Ultrasound examination showed a relatively ill-defined thickening of the skin and underlying subcutaneous tissue corresponding to the visible and palpable nodule, measuring 8 mm in diameter and 3 mm in thickness. There was no evidence of vascularity with Doppler ultrasound and no underlying fluid collection or discrete mass. The underlying musculo-tendinous structures were unremarkable (Figure 2). Histopathology of a punch biopsy is shown in Figure 3.

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Precalcaneal Congenital Fibrolipomatous Hamartoma

Cited by 3 publications

References 7 publications

Precalcaneal congenital fibrolipomatous hamartoma: Rare or under‐reported?

Precalcaneal congenital fibrolipomatous hamartoma: Rare or under‐reported?

Cutaneous fibrolipomatous hamartoma: Report of 2 cases with retrocalcaneal location

A plantar subcutaneous nodule in a healthy infant

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