The hot deformation behavior of Ti-10V-2Fe-3Al alloy obtained by the powder metallurgy (PM) method was investigated. Material for the research was produced by blending of elemental powders followed by uniaxial hot pressing. Thermomechanical tests of Ti-10V-2Fe-3Al compacts were carried out to determinate the stress-strain relationships at the temperature range of 800°C to 1000°C and strain rate between 0.01 and 10 s À1. Based on the dynamic material model (DMM) theory, processing maps at constant strain value were developed using data obtained from hot compression tests. The processing maps were elaborated for the final strain value, which was 0.9, and with flow instability criterion domains applied to it. Two critical regions associated with the flow behavior of the investigated material were revealed. Microstructural changes during hot deformation at various temperatures and strain rates were discussed. The correlation between calculated efficiency of power dissipation, flow instability criterion, and microstructure evolution was determined. The presence of defects was confirmed in regions predicted by the instability maps. The microstructure of the investigated alloy, corresponding to the high efficiency of power dissipation characterized by the occurrence of dynamic recrystallization (DRX) phenomena, was also shown. Additionally, average hardness values in relation to variable process parameters were designated. Based on the conducted studies and analysis, processing windows for Ti-10V-2Fe-3Al alloy compacts were proposed.