In 2017, the BESIII Collaboration announced the observation of a charged charmonium-like structure in the ψ(3686)π ± invariant mass spectrum of the e + e − → ψ(3686)π + π − process at different energy points, which enables us to perform a precise study of this process based on the initial single pion emission (ISPE) mechanism. In this work, we perform a combined fit to the experimental data of the cross section of e + e − → ψ(3686)π + π − , and the corresponding ψ(3686)π ± and dipion invariant mass spectra. Our result shows that the observed charged charmoniumlike structure in e + e − → ψ(3686)π + π − can be well reproduced based on the ISPE mechanism, and that the corresponding dipion invariant mass spectrum and cross section can be depicted with the same parameters. In fact, it provides strong evidence that the ISPE mechanism can be an underlying mechanism resulting in such novel a phenomenon.