2004
DOI: 10.1108/13552540410512525
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Precision extruding deposition and characterization of cellular poly‐ε‐caprolactone tissue scaffolds

Abstract: Successes in scaffold guided tissue engineering require scaffolds to have speci c macroscopic geometries and internal architectures to provide the needed biological and biophysical functions. Freeform fabrication provides an effective process tool to manufacture many advanced scaffolds with designed properties. This paper reports our recent study on using a novel precision extruding deposition (PED) process technique to directly fabricate cellular poly-ecaprolactone (PCL) scaffolds. Scaffolds with a controlled… Show more

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Cited by 217 publications
(126 citation statements)
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“…Also around this time, the first uses of XCT for inspection of AM parts were taking place. In the paper by Wang et al [35], the authors performed XCT measurements of FDM scaffolds, proving the concept of XCT as a method of non-destructive evaluation (NDE) to measure internal morphology and porosity. Similarly, Williams et al [36] performed XCT on polycaprolactone SLS scaffolds to create finite element analysis (FEA) models and to measure porosity, as well as to inspect scaffolds post-implantation (see Fig.…”
Section: History 1995-2005mentioning
confidence: 99%
“…Also around this time, the first uses of XCT for inspection of AM parts were taking place. In the paper by Wang et al [35], the authors performed XCT measurements of FDM scaffolds, proving the concept of XCT as a method of non-destructive evaluation (NDE) to measure internal morphology and porosity. Similarly, Williams et al [36] performed XCT on polycaprolactone SLS scaffolds to create finite element analysis (FEA) models and to measure porosity, as well as to inspect scaffolds post-implantation (see Fig.…”
Section: History 1995-2005mentioning
confidence: 99%
“…(1) To overcome such problems, previous studies (Greulich et al, 1995;Landers and Mülhaupt, 2000;Xiong et al, 2002;Wang et al, 2004;Woodfield et al, 2004;Narayan, 2014) developed a series of nozzle-based RP techniques based on FDM (Fig. 6).…”
Section: Fused Deposition Modelingmentioning
confidence: 99%
“…6). 3D fiber deposition, precise extrusion manufacturing (PEM), precision extrusion deposition (PED), and multi-head deposition system (MHDS) tried changing pressure-driven methods (Woodfield et al, 2004), shapes of materials (Wang et al, 2004) and extrusion methods , and they have been employed to optimize micropore formation. Such methods have improved the efficiency and reproducibility of manufacturing scaffolds with better biocompatibility for bone tissue engineering.…”
Section: Fused Deposition Modelingmentioning
confidence: 99%
“…Now-a-days CAD is being extensively used in biomedical engineering. [8,[10][11] This development is due to advances in imaging technologies including computed tomography (CT), magnetic resonance imaging (MRI), micro CT and optical microscopy. Data derived from these technologies, computer models have been reported in published literature [8,[12][13] for simulation of human bone joints, designing implants & scaffolds etc.…”
Section: Bio-cad Modelingmentioning
confidence: 99%