2023
DOI: 10.18311/ti/2023/v30i4/34635
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Preclinical Animal Models of Renal Disease

Kunal Bahalkar,
Manish Musale,
Jagdish Kakadiya

Abstract: Acute Renal Failure (ARF) is a serious condition where the kidneys suddenly stop working, commonly caused by drug-related injury. This article aims to give a detailed explanation of different animal models used to study ARF, focusing on the biomarkers linked with this condition. When administering drugs to animals, it is essential to be mindful of the potential for ARF to occur. Nephrotoxic drugs like cisplatin, methotrexate, acyclovir, Cyclosporine, folic acid, amphotericin B, and amikacin can induce ARF if t… Show more

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