Preclinical glioma models in neuro-oncology: enhancing translational research
Serena Barachini,
Mariangela Morelli,
Orazio Santo Santonocito
et al.
Abstract:Purpose of review
Gliomas represent approximately 25% of all primary brain and other central nervous system (CNS) tumors and 81% of malignant tumors. Unfortunately, standard treatment approaches for most CNS cancers have shown limited improvement in patient survival rates.
Recent findings
The current drug development process has been plagued by high failure rates, leading to a shift towards human disease models in biomedical research. Unfortunately, sui… Show more
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