Preclinical Safety Evaluation of Acute and Subacute Intranasal Administration of Polyphenols-based Cinnamon Bark Extract in Laboratory Rats

Abstract

were fed on pelleted feed (Altromin Spezialfutter GmbH and Co. KG, Germany, supplied by ATNT Laboratories, Mumbai, India) and provided with pure potable water in sterilized bottles with stainless steel sipper tubes. The rats were maintained at ambient temperature (19-25°C) and relative humidity (30-70%) with 12 h: 12 h of the dark: light cycle. The female rats were nulliparous and non-pregnant. The study