Preclinical toxicity study of Datura metel L. based Unani formulation Habb-e-Zeequn Nafas used in the treatment of Asthma

Ethnobotanical uses and phytochemical, biological, and toxicological profiles of Datura metel L.: A review

“…A unani drug for asthma named Habb-e-Zeequn Nafas (HZN), where D. metel is used as the active ingredient, was found to be safer in pre-clinical tests ( Firdaus et al, 2022 ). A newly isolated glycoside from D. metel roots (methyl 3,4-dihydroxyphenylacetate-4-O-[2-O-β-D-apisoyl-6-O-(2-hydroxybenzoyl)]-β-D-glucopyranoside) has anti-inflammatory activity ( Qin et al, 2021 ).…”