Preconcentration of plutonium and americium using the Actinide-CUTM Resin for human tissue analysis

Abstract

A method for the preconcentration of Am and Pu from human tissue solutions (liver, lung, bone etc) using the Actinide-CU Resin (EIChroM Industries) has been developed for their alpha-spectrometric determination. With near 100% recoveries were obtained by preconcentration, subsequent decomposition methods for eluent were developed. Good agreement for Pu and Am determination with the USTUR anionexchange/solvent extraction method was demonstrated using previously analyzed human tissue solutions and NIST SRMs. The advantages of the preconcentration method applied to human tissue analysis are simplicity of operation, shorter analysis time compared to anion exchange/solvent extraction methods, and capacity to analyze large tissue samples (up to 15 g bone ash per analysis and 500 g soft tissue).

Determination of Transuranium Isotopes (Pu, Np, Am) by Radiometric Techniques: A Review of Analytical Methodology

“…Because of the high selectivity of the resin for Pu(IV), very often a single chromatographic separation provides sufficient purity for the analysis. 135 Qu et al, 98 Pilvi€ o, 95 Michel et al, 29,78 Komosa et al, 136 Solatie et al, 137,55 Hrnecek et al, 34,138 Viogue et al, 139 Berlioz et al, 140 LaRosa et al, 65 Ageyev et al, 79,89 Giardina et al, 69 Lee, 131 Jakopic et al, 35 and Michel et al 78 Anion exchange procedures for Pu separation have received wide application not only in R spectrometry but in ICPMS methods (see in the monograph of Kim et al 101 ).…”

“…Recoveries of Pu, Am, and U varied in a wide range (31À91%, 22À99%, and 60À85%, respectively). ACTINIDE resin was used for the preconcentration of Pu and Am from human tissue followed by the separation of Pu with anion exchange resin by Qu et al 98 The overall recovery for Pu was high (>80%) assuring the adequacy of the preconcentration as well.…”

“…Recoveries of 89 and 83% were reported for Pu and Am, respectively. Qu et al 98 applied a similar procedure for the determination of Pu and Am in human tissue samples up to 500 g. Actinide resin was used for preconcentration, and there was no need for AmÀlanthanide separation. Recoveries were higher than 70 and 80%, respectively.…”

“…The following precipitates have been recently used to preconcentrate actinides from various samples: ferric hydroxide, ,− ferrous hydroxide, − calcium oxalate, , ferric hydroxide and calcium oxalate, ,,− calcium phosphate, ,− calcium fluoride, ,− lanthanum fluoride, , manganese dioxide, , manganese dioxide, and ferric hydroxide. − For concentration of actinides from large volume of water or solutions of biological origin, special extraction chromatographic materials of extremely high distribution coefficients have also been developed and applied, e.g., TEVA, TRU, , DIPHONIX, and DIPEX resins , (see in detail later). Smith et al developed a method for the preconcentration of Am and Pu from waste waters using a synthetic water-soluble metal-binding, for example, phosphonic acid polymer that was removed from the waste by ultrafiltration.…”

Task-Specific Supported Liquid Membrane for Actinide Assay in Aqueous Streams by Thermal Ionization Mass Spectrometry

“…However, the carbon additives TIC or PIEs serve as mere filament modifiers, and the requirement for sample pretreatment and chemical purification steps to get the analyte in the purest possible form still persists. The traditional sample preparation methods for various biological, geological, or environmental samples by TIMS are tedious and cumbersome and involve multiple steps: (i) pretreatment of aqueous/soil/sediment samples, (ii) preconcentration by either evaporation or coprecipitation, (iii) chemical purification of the analyte by solvent extraction/ion-exchange resin/extraction chromatography − (using TEVA, TRU, or DGA resin columns), and (iv) stripping/elution of the purified analyte and loading on a Re filament. , An alternative approach could be preconcentration of the desired analyte on a suitable solid phase substrate that can be directly loaded on a filament for TIMS analysis. Since the 1960s, there have been several reports where U and/or Pu preloaded on a single bead of Dowex or TEVA resin has been analyzed by TIMS .…”