We present the results of one year of continuous radon monitoring at Stromboli volcano collected at two automated real-time stations. These were deployed on the NE flank (at 520 m a.s.l.) and within the summit area (900 m a.s.l. an increases in radon concentrations were observed during periods of higher rainfall conditions. Therefore, trends in radon concentrations may be decoupled from those of other geochemical parameters (CO 2 fluxes and CO 2 /SO 2 plume ratios) during periods of heavy to moderate rainfalls.Multiple Linear Regression statistics (including the effects of soil temperature, atmospheric pressure and tidal forces) led us to compute the residuals given by the difference of measured and calculated 222 Rn concentrations. The cross-check between the daily measured radon activities and the absolute variations in radon residuals, for the data collected at the summit station, give us the opportunity to suggest a methodological approach that can be used in the attempt of predicting some major changes in volcanic activity.