Prediabetes, depressive and anxiety symptoms, and risk of type 2 diabetes: A community-based cohort study

Deschênes, Sonya S.; Burns, Rachel J.; Graham, Eva; Schmitz, N.

doi:10.1016/j.jpsychores.2016.08.011

Cited by 43 publications

(45 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, Dr Kawada expressed concern that the findings of the aforementioned studies 3,4 were inconsistent with the findings of our current study. 2 We do not see the previous studies as cause for concern for several reasons.…”

contrasting

confidence: 82%

“…3 Dr Kawada also refers to another prospective study from our research group that found that prediabetes with elevated depressive or anxiety symptoms was associated with an increased risk of incident diabetes over approximately 4.6 years, but that depressive and anxiety symptoms in people with normal glycemic levels were not significantly associated with an increased risk of diabetes. 4 Indeed, these two studies underscore the importance of depressive and anxiety symptoms in the management and risk of diabetes, and shed some light on potential mediators and moderators of these associations.…”

mentioning

confidence: 94%

See 1 more Smart Citation

Response to Kawada: Anxiety symptoms and functioning in patients with type 2 diabetes

Deschênes

Burns

Schmitz

2017

Journal of Diabetes

Self Cite

View full text Add to dashboard Cite

contrasting

confidence: 82%

mentioning

confidence: 94%

Response to Kawada: Anxiety symptoms and functioning in patients with type 2 diabetes

Deschênes

Burns

Schmitz

2017

Journal of Diabetes

Self Cite

View full text Add to dashboard Cite

“…Types of anxiety measurements included the assessment of non‐specific anxiety symptoms, a composite of different anxiety disorders, PTSD, phobic anxiety symptoms, panic, GAD and/or other anxiety (Table 1). Anxiety was determined using a variety of validated symptom scales 22, 23, 24, 25, 27, 28, 30, 33, 37, diagnostic interviews 26, 32, 33 and examination of medical records 31, 35, 36. Most studies examined general anxiety or defined anxiety or anxiety disorders using DSM‐V criteria 22, 24, 28, 33, 35, 37.…”

Section: Resultsmentioning

confidence: 99%

Investigating the longitudinal association between diabetes and anxiety: a systematic review and meta‐analysis

2018

View full text Add to dashboard Cite

AimPrevious research has indicated an association between diabetes and anxiety. However, no synthesis has determined the direction of this association. The aim of this study was to determine the longitudinal relationship between anxiety and diabetes.MethodsWe searched seven databases for studies examining the longitudinal relationship between anxiety and diabetes. Two independent reviewers screened studies from a population aged 16 or older that examined either anxiety as a risk factor for incident diabetes or diabetes as a risk factor for incident anxiety. Studies that met eligibility criteria were put forward for data extraction and meta‐analysis.ResultsIn total 14 studies (n = 1 760 800) that examined anxiety as a risk factor for incident diabetes and two (n = 88 109) that examined diabetes as a risk factor for incident anxiety were eligible for inclusion in the review. Only studies examining anxiety as a risk factor for incident diabetes were put forward for the meta‐analysis. The least adjusted (unadjusted or adjusted for age only) estimate indicated a significant association between baseline anxiety with incident diabetes (odds ratio 1.47, 1.23–1.75). Furthermore, most‐adjusted analyses indicated a significant association between baseline anxiety and incident diabetes. Included studies that examined diabetes to incident anxiety found no association.ConclusionsThere was an association between baseline anxiety and incident diabetes. The results also indicate the need for more research to examine the direction of association from diabetes to incident anxiety. This work adds to the growing body of evidence that poor mental health increases the risk of developing diabetes.

show abstract

“…The flow chart in Figure 1 summarized the references selection process. In total, 51 studies were finally included in the bidirectional analysis [13–63], among which, 32 studies were about the risk of diabetes in patients with depression, and 24 studies were about the risk of depression in patients with diabetes.…”

Section: Methodsmentioning

confidence: 99%

Quantitative assessment of the bidirectional relationships between diabetes and depression

Zhuang

Shen

2017

Oncotarget

View full text Add to dashboard Cite

Diabetes and depression impose an enormous public health burden and the present study aimed to assess quantitatively the bidirectional relationships between the two disorders. We searched databases for eligible articles published until October 2016. A total of 51 studies were finally included in the present bidirectional meta-analysis, among which, 32 studies were about the direction of depression leading to diabetes, and 24 studies about the direction of diabetes leading to depression. Pooled results of the 32 eligible studies covering 1274337 subjects showed that depression patients were at higher risk for diabetes (odds ratio (OR) = 1.34, 95% confidence intervals (CI) = [1.23, 1.46]) than non-depressive subjects. Further gender-subgroup analysis found that the strength of this relationship was stronger in men (OR = 1.63, 95%CI = [1.48, 1.78]) than in women (OR = 1.29, 95%CI = [1.07, 1.51]). For the direction of diabetes leading to depression, pooled data of 24 articles containing 329658 subjects showed that patients with diabetes were at higher risk for diabetes (OR = 1.28, 95%CI = [1.15, 1.42]) than non-diabetic subjects. The available data supports that the relationships between diabetes and depression are bidirectional and the overall strengths are similar in both directions. More mechanistic studies are encouraged to explore the molecular mechanisms underlying the relationships between the two diseases.

show abstract

Prediabetes, depressive and anxiety symptoms, and risk of type 2 diabetes: A community-based cohort study

Cited by 43 publications

References 39 publications

Response to Kawada: Anxiety symptoms and functioning in patients with type 2 diabetes

Response to Kawada: Anxiety symptoms and functioning in patients with type 2 diabetes

Investigating the longitudinal association between diabetes and anxiety: a systematic review and meta‐analysis

Quantitative assessment of the bidirectional relationships between diabetes and depression

Contact Info

Product

Resources

About