Prediabetes: Screening, Diagnosis, and Intervention

Watson, Cynthia

doi:10.1016/j.nurpra.2016.08.005

Cited by 13 publications

(11 citation statements)

References 10 publications

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“…Literature evidence indicates that the reported changes in these markers eventually lead to diabetes associated cardiovascular and renal complications [ 9 ]. Once diagnosed, pre-diabetes management relies on the combination of diet modification and administration of insulin sensitizers such as metformin [ 10 , 11 ]. However, over-reliance by patients on the pharmacological interventions has resulted in diet intervention being neglected and thus reducing the efficacy of the drugs [ 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

The Effects of Plant-Derived Oleanolic Acid on Selected Parameters of Glucose Homeostasis in a Diet-Induced Pre-Diabetic Rat Model

et al. 2018

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Prolonged exposure to high energy diets has been implicated in the development of pre-diabetes, a long-lasting condition that precedes type 2 diabetes mellitus (T2DM). A combination of pharmacological and dietary interventions is used to prevent the progression of pre-diabetes to T2DM. However, poor patient compliance leads to negligence of the dietary intervention and thus reduced drug efficiency. Oleanolic acid (OA) has been reported to possess anti-diabetic effects in type 1 diabetic rats. However, the effects of this compound on pre-diabetes have not yet been established. Consequently, this study sought to evaluate the effects OA on a diet-induced pre-diabetes rat model. Pre-diabetic male Sprague Dawley rats were treated with OA in both the presence and absence of dietary intervention for a period of 12 weeks. The administration of OA with and without dietary intervention resulted in significantly improved glucose homeostasis through reduced caloric intake, body weights, plasma ghrelin concentration and glycated haemoglobin by comparison to the pre-diabetic control. These results suggest that OA may be used to manage pre-diabetes as it was able to restore glucose homeostasis and prevented the progression to overt type 2 diabetes.

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Section: Introductionmentioning

confidence: 99%

The Effects of Plant-Derived Oleanolic Acid on Selected Parameters of Glucose Homeostasis in a Diet-Induced Pre-Diabetic Rat Model

et al. 2018

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“…The American Diabetes Association recommends screening for prediabetes beginning at age 45 for all adults and screening for type 2 diabetes in all asymptomatic adults who are overweight or obese. Only the American Academy of Clinical Endocrinologists calls for screening of all adults aged at least 45 and younger adults with any risk factor, regardless of body weight [27]. Incidentally, a recent investigation that utilized 1988-2012 NHANES data reported an 8.3% increase in prevalence rates for prediabetes among individuals aged at least 20 years within a healthy BMI range [8,23].…”

Section: Discussionmentioning

confidence: 99%

“…Risk factors for prediabetes and type 2 diabetes include several modifiable and non-modifiable characteristics [ 26 , 27 , 28 ]. Age and BMI are simple and easy metrics to dictate screening opportunities and are included in nearly all screening guidelines.…”

Section: Discussionmentioning

confidence: 99%

Health Insurance Is Associated with Decreased Odds for Undiagnosed Prediabetes and Type 2 Diabetes in American Adults

Mahoney

Bradley

Pitts

et al. 2020

IJERPH

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Over a third of adults in the United States have prediabetes, and many of those with prediabetes will progress to type 2 diabetes within 3–5 years. Health insurance status may factor into a proper diagnosis of prediabetes and diabetes. This study sought to determine the associations between health insurance and undiagnosed prediabetes and diabetes in a national sample of American adults. Publicly available data from 13,029 adults aged 18–64 years from the 2005–2016 waves of the National Health and Nutrition Examination Survey were analyzed. Health insurance type (Medicaid, Private, Other, None) was self-reported. Prediabetes and diabetes status were assessed with measures of self-report, glycohemoglobin, fasting plasma glucose, and two-hour glucose. Covariate-adjusted logistic models were used for the analyses. Overall, 5976 (45.8%) participants had undiagnosed prediabetes, while 897 (6.8%) had undiagnosed diabetes. Having health insurance was associated with decreased odds ratios for undiagnosed prediabetes: 0.87 (95% confidence interval (CI: 0.79, 0.95)) for private insurance, 0.84 (CI: 0.73, 0.95) for other insurance, and 0.78 (CI: 0.67, 0.90) for Medicaid. Moreover, having private health insurance was associated with 0.82 (CI: 0.67, 0.99) decreased odds for undiagnosed diabetes. Health insurance coverage and screening opportunities for uninsured individuals may reduce prediabetes and diabetes misclassifications.

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“…Bila kondisi prediabetes terus terjadi dan tidak tertangani, akan berisiko berkembang menjadi diabetes melitus hingga 12%, dan diperkirakan akan terjadi dalam kurun waktu lima tahun. 2,3 Setiap tahunnya, sekitar 5% -10% orang yang menderita prediabetes akan berkembang menjadi DM tipe 2. 4,3,5 Menurut Dinas Kesehatan Provinsi Jawa Tengah Tahun 2015, DM termasuk 5 kasus tertinggi penyakit tidak menular dan berada pada peringkat kedua setelah hipertensi.…”

Section: Pendahuluanunclassified

Hubungan Asupan Vitamin C, Vitamin E Dan Β-Karoten Dengan Kadar Gula Darah Puasa Pada Wanita Usia 35-50 Tahun

2018

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Latar Belakang : Vitamin C, vitamin E dan β-karoten, yang merupakan bagian dari antioksidan non-enzimatik, memiliki peran besar dalam membantu melawan radikal bebas atau Reactive Oxygen/ Nitrogen Species (ROS/ RNS) yang menyerang tubuh. Vitamin C, vitamin E dan β-karoten dapat membantu dalam mengurangi risiko terjadinya resistensi insulin akibat dari ROS/ RNS yang merusak sel β pankreas. Tujuan penelitian adalah mengetahui hubungan asupan vitamin C, vitamin E dan β-karoten dengan kadar gula darah puasa pada wanita usia 35-50 tahun.Metode : Penelitian ini merupakan penelitian observasional dengan rancangan cross sectional. Tiga puluh dua subjek dipilih dengan metode consecutive sampling. Data asupan diperoleh melalui Semi Quantitative Food Frequency Questionnaire, kadar gula darah diuji dengan metode Glucose Oxidation, dan data aktivitas fisik diperoleh melalui International Physical Activity Questionnaire- Long Form. Data dianalisis menggunakan uji Rank-Spearman.Hasil : Rerata kadar gula darah puasa subjek 99,50±23,91 mg/dL dengan rerata asupan vitamin C 187,06±160,27 mg, vitamin E 9,18±4,46 mg dan β-karoten 13,32±12,86 mg. Sebesar 78,12% subjek memiliki asupan vitamin E yang kurang; 87,5% subjek dan 71,87% subjek memiliki asupan vitamin C dan β-karoten yang cukup.Simpulan : Tidak terdapat hubungan asupan vitamin C, vitamin E dan β-karoten dengan kadar gula darah puasa pada wanita usia 35-50 tahun.

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Prediabetes: Screening, Diagnosis, and Intervention

Cited by 13 publications

References 10 publications

The Effects of Plant-Derived Oleanolic Acid on Selected Parameters of Glucose Homeostasis in a Diet-Induced Pre-Diabetic Rat Model

The Effects of Plant-Derived Oleanolic Acid on Selected Parameters of Glucose Homeostasis in a Diet-Induced Pre-Diabetic Rat Model

Health Insurance Is Associated with Decreased Odds for Undiagnosed Prediabetes and Type 2 Diabetes in American Adults

Hubungan Asupan Vitamin C, Vitamin E Dan Β-Karoten Dengan Kadar Gula Darah Puasa Pada Wanita Usia 35-50 Tahun

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