Predicted Values for Clinical Exercise Testing^1–3

Abstract

Following thorough evaluation at rest, 265 of 400 current or ex-shipyard workers rode a cycle ergometer with equal work increments each minute to exhaustion while continuous multiple noninvasive cardiorespiratory measures and intermittent intra-arterial blood pressure and blood gas measures were made. Seventy-seven men, with a mean age of 54, including some who were smokers, obese, or hypertensive, were judged to have normal cardiorespiratory systems based on history, physical, electrocardiogram during rest and exercise, chest X-ray, pulmonary function tests, and exercise performance. Their responses to exercise are given. It was unusual to find at maximal exercise a breathing reserve less than 11 L/min, arterial PO2 less than 80 mm Hg, alveolar-arterial PO2 difference greater than 38 mm Hg, arterial-end tidal PCO2 difference greater than 1 mm Hg, respiratory frequency greater than 60, or a dead space/tidal volume ratio greater than 0.28. The normal anaerobic threshold/maximal O2 uptake ratio exceeded 40%. With maximal exercise, the intra-arterial systolic and diastolic pressures rose an average of 68 and 13 mm Hg, respectively. For predicting maximal oxygen uptake and oxygen pulse in an overweight man, we find it preferable to use age and height rather than age and weight.

Recommendations on the use of exercise testing in clinical practice

“…The behaviour of PAa,O 2 during exercise cannot be predicted from resting lung function; it has to be measured. Normally Pa,O 2 does not decrease during exercise and PA-a,O 2 at peak exercise remains below 2.66-3.99 kPa (20-30 mmHg) [48,49]. A PA-a,O 2 .3.99 kPa (30 mmHg) at peak exercise is defined as abnormal and is commonly accompanied by arterial desaturation (i.e.…”

Cardiopulmonary exercise function among patients undergoing transcatheter pulmonary valve implantation in the US Melody valve investigational trial

“…Values for VO 2 were indexed to body weight and expressed as percentage of predicted values for healthy age-and gender-matched subjects as reported in previous studies with a similar protocol. 13,14 The ratio of V E to VCO 2 (V E /VCO 2 ratio) was measured at the ventilatory anaerobic threshold. The respiratory exchange ratio (RER; VCO 2 /VO 2 ratio) was measured continuously.…”

Peak Oxygen Consumption as a Predictor of Death in Patients With Heart Failure Receiving β-Blockers

“…18 Data assembly and basic statistical comparisons were performed with SAS software (version 9.1, SAS Institute). Survival curves and Cox proportional hazards analyses were performed with Harrell's Design and Hmisc libraries 19 of the S-plus 6.2 software package (Insightful, Inc).…”