Background: Academic environment and approach to learning play a significant role in academic achievement. In this study, we aimed to assess the educational environment and approach to learning in the clinical phase medical students. Subjects and Methods: This comparative cross-sectional study conducted among 59 medical students in Omdurman Islamic University from June to August 2016. Participants signed a written informed consent then responded to a structured questionnaire to collect demographic data, the DREEM, and the two process study questionnaire. The local ethical committee approved the research, and the Statistical Package for Social Sciences was for data analysis. Results: They were 59 medical students, 40.5% were males with a mean age of 22.62±1.84 years, the students perceived the learning environment as more positive than negative (114.61±20.30 out of 200), 31.4% and 31.4% had concerns about the atmosphere and social environment respectively. The participants used an in-depth approach more than superficial (29.49±6.39 vs. 22.81±6.94), the females had a more positive perception of the academic environment than males and used the superficial approach less with significant statistical difference (P-value < 0.05). Conclusion: Medical students perceived the academic environment as more positive and deep approach to learning more with room for more improvement.