“… 23 Metascience studies suggest that the discrepancy between preprints and peer-reviewed articles is small and the quality of reporting is within comparable range, supporting the validity of communicating research findings in preprints before review. 24 , 25 The results of our study and others 24 , 25 , 26 , 27 , 28 , 29 , 30 suggest that the reliability of data reported in preprints is generally high. Although there are measurable effects on research articles after peer review, such as the observed reduction in CIs, effect sizes are small.…”