Predicting children’s behaviour during dental treatment under oral sedation

Lourenço-Matharu, Liège; McIntosh, Arathi Papineni; Lo, Jessica

doi:10.1007/s40368-015-0205-9

Cited by 5 publications

(6 citation statements)

References 24 publications

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“…As described by Clark and Brunick [ 65 ], among NOIS contraindications, there is an inability to understand the procedure, the unwillingness to consent to procedure, the impossibility of establishing communication, and patients who are completely uncooperative (e.g., extreme claustrophobia, psychosomatic behavior problems, inflexible temperament [ 66 ] and extremely high anxiety before treatment [ 67 ]). The importance of patient selection with NOIS is also underlined by other authors [ 66 67 68 ], specifying, for example, that NOIS efficacy is low in cases of severe anxiety or fear [ 69 70 ]. These characteristics seem to be compatible with the patients included in the previously described RCTs [ 13 46 49 ], that recorded the lowest efficacy rates in this review.…”

Section: Discussionmentioning

confidence: 99%

Success rate of nitrous oxide-oxygen procedural sedation in dental patients: systematic review and meta-analysis

Rossit

Gil-Manich

Ribera-Uribe

2021

J Dent Anesth Pain Med

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The aim of this systematic review was to determine the success rate of nitrous oxide-oxygen procedural sedation (NOIS) in dentistry. A systematic digital search was conducted for publications or reports of randomized controlled trials evaluating the clinical performance of NOIS. Abstracts of research papers were screened for suitability, and full-text articles were obtained for those who met the inclusion and exclusion criteria accordingly. The quality of the studies was assessed using the revised Cochrane risk-of-bias tool (RoB 2). A total of 19 articles (eight randomized clinical trials with parallel intervention groups and 11 crossover trials), published between May 1988 and August 2019, were finally selected for this review. The studies followed 1293 patients reporting NOIS success rates, with a cumulative mean value of 94.9% (95% CI: 88.8–98.9%). Thirteen trials were conducted on pediatric populations (1098 patients), and the remaining six were conducted on adults (195 patients), with cumulative efficacy rates of 91.9% (95% CI: 82.5–98.1%) and 99.9% (95% CI: 97.7–100.0%), respectively. The difference was statistically significant (P = 0.002). Completion of treatment and Section IV of the Houpt scale were the most used efficacy criteria. Within the limitations of this systematic review, the present study provides important information on the efficacy rate of NOIS. However, further well-designed and well-documented clinical trials are required and there is a need to develop guidelines for standardization of criteria and definition of success in procedural sedation. Currently, completion of treatment is the most used parameter in clinical practice, though many others also do exist at the same time. To maximize NOIS efficacy, clinicians should strictly consider appropriate indications for the procedure.

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Section: Discussionmentioning

confidence: 99%

Success rate of nitrous oxide-oxygen procedural sedation in dental patients: systematic review and meta-analysis

Rossit

Gil-Manich

Ribera-Uribe

2021

J Dent Anesth Pain Med

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“…Additionally, as we aimed to deliver moderate sedation, children’s psychological characteristics might have influenced their behavior even during sedation [30–32], but the literature is scarce on this kind of investigation. Ultimately, considering the extreme negative behavior observed in some children while they were sedated, we should speculate that they would be better indicated to general anesthesia [33].…”

Section: Discussionmentioning

confidence: 99%

Randomized clinical trial on the efficacy of intranasal or oral ketamine-midazolam combinations compared to oral midazolam for outpatient pediatric sedation

et al. 2019

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PurposeThe optimal sedative regime that provides the greatest comfort and the lowest risk for procedural sedation in young children remains to be determined. The aim of this randomized, blinded, controlled, parallel-design trial was to evaluate the efficacy of intranasal ketamine and midazolam as the main component of the behavioral guidance approach for preschoolers during dental treatment.Materials and methodsChildren under seven years of age, with caries and non-cooperative behavior, were randomized into three groups: (KMIN) intranasal ketamine and midazolam; (KMO) oral ketamine and midazolam; or (MO) oral midazolam. The dental sedation appointments were videotaped, and the videos were analyzed using the Ohio State University Behavioral Rating Scale (OSUBRS) to determine the success of the sedation in each group. Intra- and postoperative adverse events were recorded. Data analysis involved descriptive statistics and non-parametric tests (P < 0.05, IBM SPSS).ResultsParticipants were 84 children (28 per group; 43 boys), with a mean age of 3.1 years (SD 1.2). Children’s baseline and the dental sedation session characteristics were balanced among groups. The success of the treatment as assessed by the dichotomous variable ‘quiet behavior for at least 60% of the session length’ was: KMIN 50.0% (n = 14; OR 2.10, 95% CI 0.71 to 6.30), KMO 46.4% (n = 13; OR 1.80, 95% CI 0.62 to 5.40), MO 32.1% (n = 9) (P = 0.360). Adverse events were minor, occurred in 37 of 84 children (44.0%), and did not differ among groups (P = 0.462).ConclusionAll three regimens provided moderate dental sedation with minor adverse events, with marked variability in the behavior of children during dental treatment. The potential benefit of the ketamine–midazolam combination should be further investigated in studies with larger samples.Trial registrationClinicalTrials.gov, identifier: NCT02447289. Registered on 11 May 2015, named “Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment (NASO).”

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“…For a number of years, sedative techniques have been employed for CT/MRI scanning and other non‐painful procedures such as transthoracic echocardiography, where the main reason for drug administration is to ensure that the baby or child remains calm and still in order to obtain excellent and complete scans. The attitude, behaviour and expectation of both the child and their carer is vital to success and the use of play therapy, as well as other techniques such as utilisation of smart phone applications , have been shown to increase success rates.…”

Section: Determining the Correct Procedures And Patient Selectionmentioning

confidence: 99%

Sedation in children - is it time to change our practice?

Bailey

2016

Anaesthesia

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Predicting children’s behaviour during dental treatment under oral sedation

Abstract: CFSS-DS may be used preoperatively to help predict behaviour outcome when children are treated under oral sedation and facilitate treatment planning.

Cited by 5 publications

References 24 publications

Success rate of nitrous oxide-oxygen procedural sedation in dental patients: systematic review and meta-analysis

Success rate of nitrous oxide-oxygen procedural sedation in dental patients: systematic review and meta-analysis

Randomized clinical trial on the efficacy of intranasal or oral ketamine-midazolam combinations compared to oral midazolam for outpatient pediatric sedation

Sedation in children - is it time to change our practice?

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