Predicting children's quality of life in an asthma clinical trial: What do children's reports tell us?

Annett, Robert D.; Bender, Bruce G.; Lapidus, Jodi; DuHamel, Thomas R.; Lincoln, Alan J.

doi:10.1067/mpd.2001.119444

Cited by 76 publications

(73 citation statements)

References 19 publications

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“…Of the studies examined for this review, all used a comparative study design (Annett et al, 2001;Blandon Vijil et al, 2004;Friedlander et al, 2003;Gibson, Henry et al, 1995;Okelo et al, 2004;Pinhas-Hamiel et al, 2006;Ravens-Sieberer et al, 2001;Schwimmer et al, 2003;Swallen et al, 2005;van Gent et al, 2007;Williams et al, 2005). Comparative designs are hypothesis-testing approaches designed to build support for theory (Brink & Wood, 1998).…”

Section: Review Of Methodologymentioning

confidence: 99%

“…The independent variables, weight/height (BMI) and asthma severity cannot be deliberately manipulated. Only three of the studies (Annett et al, 2001;Friedlander et al, 2003;Swallen et al, 2005) reviewed used random sampling for selection of subjects. However, over half of the studies reviewed used a control group for comparison (Friedlander et al, 2003;Gibson, Henry et al, 1995;Pinhas-Hamiel et al, 2006;Schwimmer et al, 2003;Swallen et al, 2005;van Gent et al, 2007;Williams et al, 2005).…”

Section: Review Of Methodologymentioning

confidence: 99%

“…In a study, by Annett, Bender, Lapidus, DuHamel, & Lincoln (2001), the researchers examined the relationship between quality of life and asthma using 339 subjects from a larger clinical trial, the Childhood Asthma Management Program (CAMP), which examined children with mild to moderate asthma (mean age, 9.3 years). The children in the study had mild asthma symptoms during the 2 weeks before their 12-month follow-up clinic visits.…”

Section: Quality Of Life In Children With Asthmamentioning

confidence: 99%

“…However, quality of life research involving asthma in children has received little attention even though asthma is the number one chronic illness among children and the number one cause of hospitalization (Mannino et al, 2002). The majority of the limited number of studies examing quality of life in asthmatic children have used the PAQLQ to measure QOL and have found only minimal to moderate impairment (Annett et al, 2001;Gibson, Henry et al, 1995). These studies have shown that QOL is a good indicator of health behaviors.…”

Section: Asthma and Qolmentioning

confidence: 99%

“…Overall, childhood asthma has been found to have a minimal effect on QOL (Annett, Bender, Lapidus, Duhamel, & Lincoln, 2001;Gibson, Henry, Vimpani, & Halliday, 1995;Okelo et al, 2004). Conversely, childhood obesity has been found to have a profound negative impact on QOL (Friedlander, Larkin, Rosen, Palermo, & Redline, 2003;Schwimmer, Burwinkle, & Varni, 2003;Williams, Wake, Hesketh, Maher, & Waters, 2005).…”

Section: Introduction Statement Of the Problemmentioning

confidence: 98%

See 4 more Smart Citations

Quality of Life and Health Outcomes in Overweight and Non-Overweight Children With Asthma

Manion¹,

Velsor-Friedrich²

2017

Journal of Pediatric Health Care

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Section: Review Of Methodologymentioning

confidence: 99%

Section: Review Of Methodologymentioning

confidence: 99%

Section: Quality Of Life In Children With Asthmamentioning

confidence: 99%

Section: Asthma and Qolmentioning

confidence: 99%

Section: Introduction Statement Of the Problemmentioning

confidence: 98%

See 3 more Smart Citations

Quality of Life and Health Outcomes in Overweight and Non-Overweight Children With Asthma

Manion¹,

Velsor-Friedrich²

2017

Journal of Pediatric Health Care

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Psychological interventions for children with asthma

Yorke

Fleming

Shuldham

2005

Cochrane Database of Systematic Reviews

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BackgroundAsthma is a chronic disease of inflammation and smooth muscle dysfunction, including bronchoconstriction. These symptoms are usually associated with widespread but variable airflow obstruction that is o en reversible either spontaneously or with treatment. Psychological factors may influence the symptoms and management of asthma in children in many ways, for example, evidence suggests that emotional stress can either precipitate or exacerbate both acute and chronic asthma. ObjectivesTo assess the e icacy of psychological interventions in improving health and behavioural outcomes for children with asthma. Search methodsThe Cochrane Airways Group Specialised Register and PsycINFO were searched with pre-defined terms up until April 2007. Selection criteriaRandomised controlled trials published in any language assessing the e ects of a psychological intervention compared with a control intervention in children and adolescents with asthma were included in the review. Cross-over trials were considered inappropriate for studies using psychological interventions and were therefore excluded from this systematic review. Data collection and analysisTwo reviewers assessed the relevance of abstracts identified by electronic searching and retrieved agreed studies for further scrutiny. The studies that met the inclusion criteria were assembled and data extracted. Main resultsTwelve studies (588 children) were included in the review. Study quality was poor and sample sizes were frequently small. A meta-analysis was possible on two studies only examining the e ects of relaxation therapy on PEFR which favoured the treatment group (32 L/min, 95% CI 13 to 50 L/min). No other meta-analysis could be performed due to the diversity of interventions and the outcomes assessed. In addition, many studies reported insu icient data.

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Nedocromil sodium for chronic asthma in children

Sridhar

McKean

2006

Cochrane Database of Systematic Reviews

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A limited number of small studies have shown that nedocromil is of benefit in improving lung function and some measures of symptoms, but the evidence with regard to the primary outcome of the review was conflicting. Two long-term trials did not show consistent effects on lung function outcomes, whereas several small short-term trials have shown benefit in these outcomes. Differing severities at baseline may explain this difference with milder participants experiencing less benefit, although the discrepancy between study findings may also reflect publication bias. Nedocromil sodium is associated with a very good safety profile with no significant short term or long- term adverse side effects. Although nedocromil may have advantages over inhaled corticosteroids in terms of side effects, there is a need for head to head trials of nedocromil and inhaled corticosteroids to establish whether asthma control is similar, especially in mild asthma. It is not yet clear where nedocromil should sit in relation to other therapies in the treatment of asthma in children.

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Predicting children's quality of life in an asthma clinical trial: What do children's reports tell us?

Cited by 76 publications

References 19 publications

Quality of Life and Health Outcomes in Overweight and Non-Overweight Children With Asthma

Quality of Life and Health Outcomes in Overweight and Non-Overweight Children With Asthma

Psychological interventions for children with asthma

Nedocromil sodium for chronic asthma in children

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