Predicting drying kinetic and undesired agglomeration during drying of granules containing amorphous water-soluble substances in a continuous horizontal fluid bed dryer

Palzer, Stefan

doi:10.1016/j.powtec.2010.03.019

“…In the literature [ 14 , 15 ], more detailed models on the energy and mass transfer are given, which might improve the model accuracy. However, as the prediction performance of the presented model was satisfactory, and in order to keep the model simple, the strongly simplified phenomenological approach given by Equations (21)–(23) was chosen.…”

Section: Methodsmentioning

confidence: 99%

End-Point Prediction of Granule Moisture in a ConsiGmaTM-25 Segmented Fluid Bed Dryer

Rehrl

¹

,

Sacher

²

,

Horn

³

et al. 2020

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Continuously operated pharmaceutical manufacturing lines often consist of a wet granulation unit operation, followed by a (semi-) continuous dryer. The operating conditions of the dryer are crucial for obtaining a desired final granule moisture. Commercially available dryers lack of a thorough online measurement of granule moisture during the drying process. However, this information could improve the operation of the equipment considerably, yielding a granule moisture close to the desired value (e.g., by drying time and process parameter adjustments in real-time). The paper at hand proposes a process model, which can be parameterized from a very limited number of experiments and then be used as a so-called soft sensor for predicting granule moisture. It utilizes available process measurements for the estimation of the granule moisture. The development of the model as well as parameter identification and validation experiments are provided. The proposed model paves the way for the application of sophisticated observer concepts. Possible future activities on that topic are outlined in the paper.

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“…The drying is a basic operation of enormous commercial importance in all industrial applications ranging through the food, agricultural, mining and even manufacturing sectors [1]. Modern societies need better product quality, enhanced safety practices and more environmentally benign operations as well as higher productivity, better energy yield and reduced material wastage, also [2].…”

Section: Introductionmentioning

confidence: 99%

Untitled

2017

JABB

0

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This work presents the effective optimum parameters of one rotary dryer such as energy consumption, optimum drying time, color and size distribution of outlet sodium chloride crystals from dryer and the amount of distilled water. The experimental results show, the maximum deviation between salt production in 12 minutes as drying time and production of dried saline crystals in 15.2 minutes is only 8% but since of the quality of outlet dried saline crystals is optimized in 15.2 minutes so this drying time is introduced as optimized time for drying. Also, the moisture content (kg) per dried salt (kg) in this condition is 0.005. According to the literature, this amount of moisture content in outlet dried saline crystals is very suitable.

show abstract

“…The drying is a basic operation of enormous commercial importance in all industrial applications ranging through the food, agricultural, mining and even manufacturing sectors [1]. Modern societies need better product quality, enhanced safety practices and more environmentally benign operations as well as higher productivity, better energy yield and reduced material wastage, also [2].…”

Section: Introductionmentioning

confidence: 99%

The Experimental Survey on the Rotary Dryer Performance: Drying of Wetted Salt from Effluent Bio Wastewater

Jafari

¹

,

Farahbod

²

2017

JABB

3

0

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This work presents the effective optimum parameters of one rotary dryer such as energy consumption, optimum drying time, color and size distribution of outlet sodium chloride crystals from dryer and the amount of distilled water. The experimental results show, the maximum deviation between salt production in 12 minutes as drying time and production of dried saline crystals in 15.2 minutes is only 8% but since of the quality of outlet dried saline crystals is optimized in 15.2 minutes so this drying time is introduced as optimized time for drying. Also, the moisture content (kg) per dried salt (kg) in this condition is 0.005. According to the literature, this amount of moisture content in outlet dried saline crystals is very suitable.

show abstract

Predicting drying kinetic and undesired agglomeration during drying of granules containing amorphous water-soluble substances in a continuous horizontal fluid bed dryer

Cited by 4 publications

References 14 publications

End-Point Prediction of Granule Moisture in a ConsiGmaTM-25 Segmented Fluid Bed Dryer

End-Point Prediction of Granule Moisture in a ConsiGmaTM-25 Segmented Fluid Bed Dryer

Untitled

The Experimental Survey on the Rotary Dryer Performance: Drying of Wetted Salt from Effluent Bio Wastewater

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