Abstract:Successful Prediction for MHC Class II epitopes is an essential step in designing Genetic Vaccines[1]. MHC Class II epitopes are short peptides with length between 9 and 25 amino acids which are bound by MHC. These epitopes are recognized by T-Cell Receptors and leads to activation of cellular and humoral immune system and, ultimately, to effective destruction of pathogenic organism. Successful prediction of MHC class II epitopes is more difficult than MHC class I epitopes due to open binding groove at both en… Show more
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