Predicting Nonunions in Ankle Fractures Using Quantitative Tibial Hounsfield Samples From Preoperative Computed Tomography: A Multicenter Matched Case Control Study

Stowers, Jered M.; Black, Alexandra T.; Kavanagh, Amber M.; Mata, Karla De La; Bohm, Andrew; Katchis, Stuart D.; Weiner, Lon S.; Spielfogel, William D.; Rahnama, Ali

doi:10.1053/j.jfas.2021.10.007

Cited by 8 publications

(6 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Syndesmotic involvement is associated with poor functional outcomes [ 34 ]. Precision in syndesmotic reduction is crucial for obtaining good functional outcomes and avoiding future complications.…”

Section: Discussionmentioning

confidence: 99%

Predictive Factors of Functional Outcomes and Quality of Life in Patients with Ankle Fractures: A Systematic Review

Lorente,

Pelaz,

Palacios

et al. 2024

JCM

View full text Add to dashboard Cite

Background: Evaluating the predictors of unfavorable outcomes in patients with ankle fractures is crucial for identifying high-risk patients and implementing personalized treatment strategies. This study aimed to analyze factors that influence quality of life in patients with ankle fractures. Methods: Four databases were consulted. The main outcomes were functionality and quality of life scales combined using the standard mean difference (SMD) (Review Manager 5.4). Results: Eight studies with 2486 patients were included. A significant correlation was found between female sex and worse functionality scores (beta 4.15, 95% CI 1.84–6.46). Additionally, older age was correlated with worse functionality scores (beta −0.24, 95% CI −0.29 to −0.19). Patients with diabetes or metabolic syndrome also had worse outcomes (SMD 0.27, 95% CI 0.18–0.36). High BMI and obesity were also associated with worse quality of life scores (beta 2.62, 95% CI 0.77–4.48). Smokers had greater disability in the analyzed scales (SMD 0.22, 95% CI 0.05–0.39). No significant differences were observed with respect to syndesmotic involvement. Conclusions: Age, sex, diabetes, high BMI, and smoking negatively impact functional outcomes and quality of life in patients with ankle fractures.

show abstract

Section: Discussionmentioning

confidence: 99%

Predictive Factors of Functional Outcomes and Quality of Life in Patients with Ankle Fractures: A Systematic Review

Lorente,

Pelaz,

Palacios

et al. 2024

JCM

View full text Add to dashboard Cite

show abstract

“…This is because the bone callus that forms during the healing process is initially made of soft tissue, such as cartilage and collagen fibers, which have lower HU than mature bone tissue (5,10) . To highlight the importance of the HU measurement, a recent study showed that it can be used as a predictor for nonunions in distal tibia fractures (19) .…”

Section: Discussionmentioning

confidence: 99%

Correlation between the region of interest in digital radiography, Hounsfield units, and histological maturation on Wistar rats submitted to tibial fracture

Padula,

Pires,

Babinski

2024

J Foot Ankle

View full text Add to dashboard Cite

Objective: Study the relationship between the region of interest (ROI) and Hounsfield units (HU) in the tibial bone callus. Methods: Twenty-one adult Wistar rats were submitted to tibial fracture. The fracture was radiographed after their euthanasia, and the bone calluses were analyzed histologically after being stained with hematoxylin and eosin. Euthanasia occurred between the 2nd and 6th weeks after fracture and fixation, thus obtaining various consolidation stages. Histologically, vessels, chondroblasts, connective tissue (collagen), maximum size of the chondrocyte, and the concentration of chondrocytes were quantified. Results: It was observed that the higher the HU, the more mature and closer to bone consolidation it is, proving that the use of ROI and bone callus measurement with HU is reliable for the histological process of maturation of the bone callus and can be safely used as proof of evolution of the bone healing process. Conclusion: The ROI was successfully used in digital radiography to observe HU in fractured bones. Level of Evidence IV; Therapeutic Studies; Case Series.

show abstract

“…Or perhaps it will prove advisable to use several measures simultaneously, e.g., for monitoring remodeling of the cancellous and cortical substance. It is also important to test the usefulness in other parts of skeletal surgery such as hand [60], foot [61], thoracic [62], orthognathic [63], spine [64], joint replacements [35,65] and rehabilitation [66,67].…”

Section: Discussionmentioning

confidence: 99%

Measures of Corticalization

Kozakiewicz

2022

JCM

View full text Add to dashboard Cite

After the insertion of dental implants into living bone, the condition of the peri-implant bone changes with time. Implant-loading phenomena can induce bone remodeling in the form of the corticalization of the trabecular bone. The aim of this study was to see how bone index (BI) values behave in areas of bone loss (radiographically translucent non-trabecular areas) and to propose other indices specifically dedicated to detecting corticalization in living bone. Eight measures of corticalization in clinical standardized intraoral radiographs were studied: mean optical density, entropy, differential entropy, long-run emphasis moment, BI, corticalization index ver. 1 and ver. 2 (CI v.1, CI v.2) and corticalization factor (CF). The analysis was conducted on 40 cortical bone image samples, 40 cancellous bone samples and 40 soft tissue samples. It was found that each measure distinguishes corticalization significantly (p < 0.001), but only CI v.1 and CI v.2 do so selectively. CF or the inverse of BI can serve as a measure of peri-implant bone corticalization. However, better measures are CIs as they are dedicated to detecting this phenomenon and allowing clear clinical deduction.

show abstract

Predicting Nonunions in Ankle Fractures Using Quantitative Tibial Hounsfield Samples From Preoperative Computed Tomography: A Multicenter Matched Case Control Study

Cited by 8 publications

References 29 publications

Predictive Factors of Functional Outcomes and Quality of Life in Patients with Ankle Fractures: A Systematic Review

Predictive Factors of Functional Outcomes and Quality of Life in Patients with Ankle Fractures: A Systematic Review

Correlation between the region of interest in digital radiography, Hounsfield units, and histological maturation on Wistar rats submitted to tibial fracture

Measures of Corticalization

Contact Info

Product

Resources

About