Predicting psychological distress in patients with leukaemia and lymphoma

Montgomery, Charles; Pocock, Marilyn; Titley, Kirsten; Lloyd, Keith

doi:10.1016/s0022-3999(02)00396-3

Cited by 56 publications

(80 citation statements)

References 18 publications

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“…Several cancer clinics including lung, upper gastrointestinal, head and neck and haematological cancers were not included. As other studies have reported a high prevalence of emotional distress in patients with these cancers (Zabora et al, 2001;Montgomery et al, 2003), the findings presented may have underestimated the prevalence of clinically significant emotional distress in the whole cancer centre; (b) not all patients attending the cancer centre completed the HADS screening. New outpatient attenders were excluded at the request of the clinicians.…”

Section: Limitationsmentioning

confidence: 66%

Emotional distress in cancer patients: the Edinburgh Cancer Centre symptom study

et al. 2007

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To: (1) estimate the prevalence of clinically significant emotional distress in patients attending a cancer outpatient department and (2) determine the associations between distress and demographic and clinical variables, we conducted a survey of outpatients attending selected clinics of a regional cancer centre in Edinburgh, UK. Patients completed the Hospital Anxiety and Depression Scale (HADS) on touch-screen computers and the scores were linked to clinical variables on the hospital database. Nearly one quarter of the cancer outpatients 674 out of 3071 (22%; 95% confidence interval (CI) 20 -23%) met our criterion for clinically significant emotional distress (total HADS score 15 or more). Univariate analysis identified the following statistically significant associations: age o65, female gender, cancer type and extent of disease. Multivariate analysis indicated that age o65 (odds ratio 1.41; 95% CI 1.18 -1.69), female gender (odds ratio 1.58; 95% CI 1.31 -1.92) and active disease (odds ratio 1.72; 95% CI 1.43 -2.05) but not cancer diagnosis, were the independent predictors of clinically significant emotional distress. Services to treat distress in cancer patients should be organised to target patients by characteristics other than their cancer diagnosis.

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Section: Limitationsmentioning

confidence: 66%

Emotional distress in cancer patients: the Edinburgh Cancer Centre symptom study

et al. 2007

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“…Contudo é mais alta do que as taxas de 6% e 14% evidenciadas em duas investigações que utilizaram entrevistas estruturadas e os critérios do DSM-IV para depressão maior (Hosaka et al, 1994;Prieto et al, 2002). Por outro lado, é mais baixa que as taxas de 44%, 51% e 55%, encontradas quando foram utilizadas escalas (Hosaka et al, 1994;Hasan et al, 2003;Montgomery et al, 2003). Provavelmente as diferenças são decorrentes do modo de avaliação.…”

Section: Discussionunclassified

“…Outros estudos com critérios um pouco mais claros, mas ainda com amostras pequenas, de 31 a 51 pacientes com leucemias e linfomas, revelaram taxas de depressão que variaram de 6% a 55% (dos Santos et al, 1991;Hosaka et al, 1994;Montgomery et al, 2003). Assim, quando foi utilizada uma entrevista estruturada e os critérios da terceira revisão do Manual Diagnóstico e Estatístico de Transtornos Mentais (DSM-III-R), foi encontrada a taxa de 6% de pacientes com depressão maior e 23% com transtorno de ajustamento (Hosaka et al, 1994).…”

Section: Introductionunclassified

“…Quando foi usada a escala de Zung com o ponto de corte de 39/40, deparou-se com a taxa de 55% de sintomas depressivos (Hosaka et al, 1994). Já em outra pesquisa, através da escala hospitalar de ansiedade e depressão (HAD), verificaram-se taxas de 51% ou 14%, caso fossem utilizados os pontos de corte 13 ou 19, respectivamente (Montgomery et al, 2003). Nessa pesquisa houve associação entre idade mais avançada e depressão (Montgomery et al, 2003).…”

Section: Introductionunclassified

“…Já em outra pesquisa, através da escala hospitalar de ansiedade e depressão (HAD), verificaram-se taxas de 51% ou 14%, caso fossem utilizados os pontos de corte 13 ou 19, respectivamente (Montgomery et al, 2003). Nessa pesquisa houve associação entre idade mais avançada e depressão (Montgomery et al, 2003). Por fim, autores portugueses relataram que usaram uma entrevista semi-estruturada e os critérios do DSM-II-R, encontrando 30% de pacientes com "distúrbios adaptativos com humor depressivo ou misto (ansiedade e depressão)".…”

Section: Introductionunclassified

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Diagnosticando depressão em pacientes internados com doenças hematológicas: prevalência e sintomas associados

Furlanetto

Moral

Gonçalves

et al. 2006

J. bras. psiquiatr.

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ResumoIntrodução: Não encontramos estudos avaliando o diagnóstico e a prevalência de depressão em pacientes hematológicos aqui no Brasil. Objetivo: Verificar a prevalência dos sintomas depressivos e quais deles mais se associam à depressão em pacientes internados com doenças hematológicas. Métodos: Num estudo transversal, 104 pacientes consecutivamente internados nos leitos da hematologia do Hospital Universitário da Universidade Federal de Santa Catarina (HU/UFSC) foram avaliados. Foram preenchidos questionários de variáveis sociodemográficas e de história psiquiátrica. O índice Charlson de co-morbidade (IC) foi usado para medir gravidade física. Foi aplicado, também, o inventário Beck de depressão (BDI). Aqueles que tiveram pontuação acima de 9 na soma dos 13 primeiros itens do BDI (BDI-13) foram considerados deprimidos. Também foi verificada a freqüência caso fosse utilizada a escala completa com 21 itens (BDI-21), com ponto de corte 16/17. Resultados: As prevalências foram: BDI-13 = 25% e BDI-21 = 32,7%. Após controle para fatores de confusão, os sintomas que permaneceram no modelo da regressão logística, indicando que melhor detectavam os deprimidos, foram sensação de fracasso, anedonia, culpa e fadiga. Conclusão: Cerca de um quarto a um terço dos pacientes internados com doenças hematológicas tinham sintomas depressivos significativos, e os sintomas que melhor os discriminaram foram sensação de fracasso, anedonia, culpa e fadiga. Palavras-chave: sintomas depressivos, hematologia, pacientes internados, co-morbidade psiquiátrica, prevalência. AbstractIntroduction: We did not find studies evaluating diagnosis and prevalence of depression in patients with hematological diseases in Brazil. Objective: To verify the prevalence of depressive symptoms and to identify which of them better help discriminate hematological inpatients who are depressed. Methods: A transversal study was conducted with 104 inpatients consecutively admitted to the hematology ward of Hospital Universitário of Universidade Federal de Santa Catarina. Data on sociodemographic variables and history of psychiatric disorders were collected. The Charlson Comorbidity Index (CI) was used to measure medical comorbidity. Depressive symptoms were assessed using the Beck Depression Inventory (BDI). Those who scored above 9 in the sum of the first 13 items (BDI-13) were considered depressed. We also evaluated prevalence using all the 21 items (BDI-21), by means of a cut-off score of 16/17. Results: Prevalences were: BDI-13 = 25% and BDI-21 = 32.7%. After control for confounders, the symptoms that remained in the logistic regression model, indicating their ability to detect depressed patients, were sense of failure, anhedonia, guilt and fatigue. Conclusions: Around a quarter to a third of hematological inpatients had significant depressive symptoms and the ones that better discriminated depressed patients were sense of failure, anhedonia, guilt and fatigue.

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Factors of emotional distress in lymphoma: A systematic review

2023

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Objective Distress is prevalent among lymphoma patients/survivors. Current processes of distress identification rely on self‐reporting by patients/survivors, which may be limited by their willingness to report symptoms. To help identify patients/survivors at greater risk, this systematic review aims to comprehensively review factors that may contribute to distress in lymphoma patients/survivors. Methods PubMed was systematically searched for peer‐reviewed primary articles (1997–2022) consisting of standardised keywords “lymphoma” and “distress.” Information from 41 articles was integrated via narrative synthesis. Results Consistent risk factors of distress include younger age, relapsed disease, and greater comorbidities and symptom burden. Active treatment and the transition from treatment to post‐treatment could be challenging phases. Adequate social support, adaptive adjustment to cancer, engaging in work and healthcare professionals' support may mitigate distress. There is some evidence that older age may be associated with greater depression and life changes/experiences may shape how individuals cope with lymphoma. Gender and marital status were not robust predictors of distress. Other clinical, psychological and socioeconomic factors are understudied or have mixed findings. Conclusions While several factors of distress align with that of other cancers, more research is needed to identify significant factors of distress in lymphoma patients/survivors. The identified factors may support clinicians in identifying distressed lymphoma patients/survivors and providing interventions where necessary. The review also highlights avenues for future research and a need to routinely collect data on distress and its factors in registries.

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Predicting psychological distress in patients with leukaemia and lymphoma

Cited by 56 publications

References 18 publications

Emotional distress in cancer patients: the Edinburgh Cancer Centre symptom study

Emotional distress in cancer patients: the Edinburgh Cancer Centre symptom study

Diagnosticando depressão em pacientes internados com doenças hematológicas: prevalência e sintomas associados

Factors of emotional distress in lymphoma: A systematic review

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