Recent Advances in Noncoding RNAs 2022
DOI: 10.5772/intechopen.105514
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Predicting SNPs in Mature MicroRNAs Dysregulated in Breast Cancer

Abstract: Breast cancer (BC) is the leading type of cancer among women. Findings have revolutionized current knowledge of microRNA (miRNA) in breast tumorigenesis. The seed region of miRNA regulates the process of gene expression negatively. The presence of SNPs in the seed regions of miRNA dramatically alters the mature miRNA function. Additionally, SNPs in the out-seed region of miRNAs have a significant impact on miRNA targeting. This study focuses on the in silico analysis procedure of mature miRNA SNPs and their im… Show more

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