Predicting subjective refraction with dynamic retinal image quality analysis

Abstract

The aim of this work is to evaluate the performance of a novel algorithm that combines dynamic wavefront aberrometry data and descriptors of the retinal image quality from objective autorefractor measurements to predict subjective refraction. We conducted a retrospective study of the prediction accuracy and precision of the novel algorithm compared to standard search-based retinal image quality optimization algorithms. Dynamic measurements from 34 adult patients were taken with a handheld wavefront autorefractor and static data was obtained with a high-end desktop wavefront aberrometer. The search-based algorithms did not significantly improve the results of the desktop system, while the dynamic approach was able to simultaneously reduce the standard deviation (up to a 15% for reduction of spherical equivalent power) and the mean bias error of the predictions (up to 80% reduction of spherical equivalent power) for the handheld aberrometer. These results suggest that dynamic retinal image analysis can substantially improve the accuracy and precision of the portable wavefront autorefractor relative to subjective refraction.

Ametropia detection using a novel, compact wavefront autorefractor

“…Lastly, it is worth noting that in this preliminary assessment of the QSFree, the use of advanced algorithms, validated in prior iterations of the technology, 18,19 fell outside of the goal of this study. It is expected that machine learning approaches, when applied to the measurement data, could further improve the agreement of the objective measurements with the subjective findings.…”

“…Further details about the technical performance and custom data processing algorithms have been described previously. [15][16][17][18] F I G U R E 1 (a) Photographs of the QuickSee Free (QSFree) prototype in use. The operator places the device on the patient's face with one hand.…”

“…com/ quick see-free), which incorporates an advanced version of a well-established wavefront refraction technology. 8,11,[15][16][17][18][19] The new design of the optical system and software algorithms allow for an extended myopic measurement range and the incorporation of a pupil camera within an ultra-compact device. QSFree, unlike its predecessor QuickSee, was designed so that the operator holds the device to the patient's face to improve usability while maintaining high levels of precision and accuracy.…”

“…The current study introduces and clinically evaluates a pre‐commercial prototype of a novel handheld, open‐view, monocular Hartmann–Shack‐based autorefractor, named QuickSee Free (QSFree), manufactured by PlenOptika (http://plenoptika.com/quicksee-free), which incorporates an advanced version of a well‐established wavefront refraction technology 8,11,15–19 . The new design of the optical system and software algorithms allow for an extended myopic measurement range and the incorporation of a pupil camera within an ultra‐compact device.…”

Compact Models of Presbyopia Accommodative Errors for Wearable Adaptive-Optics Vision Correction Devices

“…In these studies, the pupil diameter is tightly controlled with the help of phenylephrine [55] in order to decouple the effects of the depth of field on the AR/ AE measurements. Therefore, such measurements cannot be directly or easily converted to subjective AR/ AE [15], [16], [19]- [23], [27], [56], [57] for practical use in autofocusing eyewear.…”