2019
DOI: 10.1177/1934578x19883071
|View full text |Cite
|
Sign up to set email alerts
|

Predicting the Mechanism of the Analgesic Property of Yanhusuo Based on Network Pharmacology

Abstract: Yanhusuo (Corydalis Rhizoma) extracts are widely used for the treatment of pain and inflammation. The effects of Yanhusuo in pain assays were assessed in a few studies. However, there are few studies on its analgesic mechanism. In this paper, network pharmacology was used to explore the analgesic components of Yanhusuo and its analgesic mechanism. The active components of Yanhusuo were screened by TCMSP database, combined with literature data. PharmMapper and GeneCards databases were used for screening the ana… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1

Citation Types

0
2
0

Year Published

2021
2021
2022
2022

Publication Types

Select...
5

Relationship

1
4

Authors

Journals

citations
Cited by 5 publications
(2 citation statements)
references
References 25 publications
0
2
0
Order By: Relevance
“…Protoberberine-type alkaloids, such as copstine, berberine, and palmatine, shown moderate inhibitory activity [ 8 ]. Natural products such as coptisine and columbamine, alkaloids extracted from Corydalis yanhusuo, can alleviate dyspepsia caused by bacterial infection [ 26 , 27 ].…”
Section: Discussionmentioning
confidence: 99%
“…Protoberberine-type alkaloids, such as copstine, berberine, and palmatine, shown moderate inhibitory activity [ 8 ]. Natural products such as coptisine and columbamine, alkaloids extracted from Corydalis yanhusuo, can alleviate dyspepsia caused by bacterial infection [ 26 , 27 ].…”
Section: Discussionmentioning
confidence: 99%
“…10 Network pharmacology is a new subject of establishing a multilevel network of diseasegene-drug; drug targets can be predicted by the network in the discovery of new drugs. 11 In present research, we used network pharmacology to study the anti-inflammatory compounds of AP and its anti-inflammatory mechanism. The anti-inflammatory compounds of AP were filtrated by TCMSP database, in combination with literature.…”
Section: Introductionmentioning
confidence: 99%