Predicting the severity of everyday functional disability in people with schizophrenia: cognitive deficits, functional capacity, symptoms, and health status

Harvey, Philip D.; Strassnig, Martin

doi:10.1016/j.wpsyc.2012.05.004

Cited by 279 publications

(255 citation statements)

References 47 publications

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“…The bottom line, however, is that these treatments are currently not adequate to promote recovery on their own or for the majority of cases. [11], just like in people without mental illness [12,13]. Poor physical health serves to shorten progressively dysfunctional lives of our patients, feeding a vicious cycle of morbidity, disability and premature death.…”

Section: Introductionmentioning

confidence: 99%

Cognitive deficits, obesity and disability in schizophrenia

Strassnig

Cáceda

Newcomer

et al. 2012

Translational Neuroscience

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Despite 50 years of pharmacological and psychosocial interventions schizophrenia remains one of the leading causes of disability. The inability to function in everyday settings includes deficits in performance of social, occupational, and independent living activities. Schizophrenia is also a life-shortening illness, caused mainly by poor physical health and its complications. Dysfunctional lifestyles including sedentary behavior and lack of physical activity prevail, while treatment with adipogenic antipsychotic medication interacts with poor performance in screening, monitoring, and intervention that result in shortening of life expectancies by 25-30 years. Disability interferes with self-care and medical care, further worsening physical health to produce a vicious cycle of disability. Further, the neurobiological impact of obesity on brain functioning is substantial and relevant to schizophrenia. Decision making deficits that lead to choices resulting in obesity themselves have neurobiological determinants. Simultaneous treatment of cognitive deficits and related deficits in functional skills, ubiquitous determinants of everyday functioning in schizophrenia, and targeted interventions aimed at poor physical health, especially obesity and associated comorbidities, may lead to additive or even interactive gains in everyday functioning in patients with schizophrenia not previously realized with other interventions.

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Section: Introductionmentioning

confidence: 99%

Cognitive deficits, obesity and disability in schizophrenia

Strassnig

Cáceda

Newcomer

et al. 2012

Translational Neuroscience

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“…Numerous studies indicate the existence of neurocognitive deficits, and they have already been unquestionably inscribed in schizophrenia [39,40]. These deficits include, inter alia, locomotor function, learning and memory, operational functions, attention, language, spatial ability and general intelligence.…”

Section: Resultsmentioning

confidence: 99%

“…Liczne badania wskazują na istnienie deficytów neuropoznawczych i zostały one już w niekwestionowany sposób wpisane w schizofrenię [39,40]. Deficyty te obejmują m. in.…”

Section: Wyniki I Dyskusjaunclassified

Review paper. Neuropsychological dimension of schizophrenia - evaluation possibilities and therapeutic implications

Makarewicz

Karakuła-Juchnowicz

Łobejko

2017

Current Problems of Psychiatry

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Introduction: In the last decades, researchers' attention has been focused on cognitive dysfunction in schizophrenia. Numerous studies indicate the existence of neurodegenerative deficits in schizophrenia including, but not limited to, motor functions, learning and memory, executive functions, attention, language, spatial skills and general intelligence.Method: A review of available literature on the topic of the past two decades, available in the Pubmed, EBSCO, SCOPUS databases has been made using the keywords: schizophrenia, cognition, early intervention.Results: Cognitive dysfunction is an important feature of the prodromal phase and the first episode of schizophrenia. Researchers have thus proposed to initiate early therapeutic interventions for people with so-called risky mental conditions. The article includes the reference to research on neurocognitive disorders essence in schizophrenia, the definition and review of methods used to identify specific cognitive deficits and issues related to risk of developing psychosis and early therapeutic intervention in high-risk states.Conclusions: Researchers report the importance of detecting cognitive disorders in the early stages of schizophrenia. This broadens the range of therapeutic interventions and enables early intervention in the increased risk of psychosis.

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“…It is common knowledge that mental illness (MI) has a marked impact on a person's daily living and modifies his/her social status [1][2][3], possibilities for interpersonal communication [4,5], family relations [6], thus leading to a decrease of physical activity and confidence in his/her abilities [7]. The above-mentioned changes are facilitated by the formation of cognitive deficiency [7,8] and the negative influence of the social environment, which often results in development of stigmatization (and self-stigmatization) [9,10], distorting, in many cases, the patient's interaction with official psychiatric services [11].…”

Section: Introductionmentioning

confidence: 99%

A Mentally Ill Patient and his/her Social Environment

Nekrasov¹

2014

Int J Biomed

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Background: Mental illness (MI) markedly affects a person's daily living and leads to disability, reduced duration of active life and, finally, tremendous economic losses incurred by the state and society. Moreover, it has an adverse impact on the patient's immediate social surroundings. The aim of the research was to study various aspects of mentally ill patients' daily living and their social environment in order to optimize psychosocial rehabilitation programs and therapies.Methods: One thousand forty two mentally ill people and 580 persons from their social environment participated in an anonymous social survey. The survey was carried out using specially developed structured questionnaires.The results showed that MI changes the quality of life of mentally ill people (MIP): impaired well-being (84.4%), curbing of interests (36.0%), increased emotional sensitivity (39.0%), low self-esteem (75.4%), problems in family relations (78.0%), dramatic loss of sexual activity (72.3%), and in 75.8% patients -stigmatizing effect of their MI. The presence of a mentally-ill member in a family significantly affected the life and inner world of people close to that member, and modified their professional activity (38.8%), daily living (56.8%) and emotional state (36.2%).Conclusion: To improve application of psychosocial rehabilitation methods, an attempt was made to conduct a comprehensive medical and social study of the mentally ill and their social environment.

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Predicting the severity of everyday functional disability in people with schizophrenia: cognitive deficits, functional capacity, symptoms, and health status

Cited by 279 publications

References 47 publications

Cognitive deficits, obesity and disability in schizophrenia

Cognitive deficits, obesity and disability in schizophrenia

Review paper. Neuropsychological dimension of schizophrenia - evaluation possibilities and therapeutic implications

A Mentally Ill Patient and his/her Social Environment

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