Predicting vertebral deformity using bone densitometry at various skeletal sites and calcaneus ultrasound

Ross, Philip D.; Huang, Chin Chou; Davis, James W.; Imose, Kazuo; Yates, John; Vogel, John M.; Wasnich, Richard D.

doi:10.1016/8756-3282(94)00045-x

Cited by 190 publications

(92 citation statements)

References 40 publications

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“…Reproducibility was 0.009 g/cm 2 for spine BMD, 0.014 g/cm for distal radius BMC, 0.015 g/cm for proximal radius BMC, 0.003 g/cm 2 for calcaneus BMD, and 3.6 dB/ MHz for calcaneus BUA measurements. 9,10 Fracture diagnosis…”

Section: Bone Density and Broadband Ultrasound Attenuation Measurementsmentioning

confidence: 99%

Factors associated with joint pain among postmenopausal women

et al. 1997

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OBJECTIVES: To investigate potential factors associated with joint pain among postmenopausal women. DESIGN: Population-based cross-sectional study. SUBJECTS: Six hundred and ninety postmenopausal Japanese±American women from the Hawaii Osteoporosis Study (age: 55±93 y). MEASUREMENTS: Data for this study were collected at the 1992±1994 examination of the Hawaii Osteoporosis Study, except that data on spinal osteoarthritis were obtained based on radiographs at examinations before 1987. Information on painful joints at a variety of skeletal sites, smoking, and physical activity was collected by questionnaire. Bone density was measured at the lumbar spine, distal and proximal radius, and heel. Quantitative bone ultrasound was also measured at the heel. Prevalent vertebral fractures were identi®ed on lateral spine radiographs using 3 s.d. below the normal population mean as the cutoff. Non-spine fractures were identi®ed based on self-report, and were veri®ed using medical records. RESULTS AND CONCLUSIONS: In this cross-sectional analysis, bone density, quantitative bone ultrasound, prevalent vertebral fractures, and non-spine fractures were not signi®cantly associated with joint pain. Greater body weight or body mass index were signi®cantly and positively associated with joint pain at most weight-bearing joints. The results suggest that a substantial proportion of joint pain at these sites could be prevented by avoidance of excess weight, provided the association is causative. Longitudinal studies are needed to con®rm the observed cross-sectional associations.

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Section: Bone Density and Broadband Ultrasound Attenuation Measurementsmentioning

confidence: 99%

Factors associated with joint pain among postmenopausal women

et al. 1997

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“…Low BMD and height loss, for example, are associated with increased vertebral fracture prevalence. (9,11,12) However, vertebral fracture causes height loss and reduced mobility, which in turn, can decrease BMD. This makes the interpretation of cross-sectional studies difficult.…”

Section: Introductionmentioning

confidence: 99%

Incidence and Risk Factors for Vertebral Fracture in Women and Men: 25-Year Follow-Up Results From the Population-Based Framingham Study

Samelson

Hannan

Zhang

et al. 2006

Journal of Bone and Mineral Research

119

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This study evaluates baseline characteristics of 704 women and men in the Framingham Study with respect to long-term risk of incident vertebral fracture. Incidence was 24% in women and 10% in men. Few factors in middle-aged persons, except prevalent (moderate) fracture and alcohol consumption (in men), predicted long-term incidence of vertebral fracture. Introduction:We studied potential risk factors in women and men in middle adult years to help identify individuals at increased long-term risk of vertebral fracture in advanced age. Materials and Methods: Participants included Framingham cohort members who underwent radiographic examinations at baseline in 1967-1969 (mean age, 53 years) and follow-up in 1992-1993. Semiquantitative methods were used to determine incident fracture, defined as any vertebral body graded normal at baseline and at least mildly deformed (20-25% reduction or more in any vertebral height) at follow-up. Information on potential risk factors was obtained from examinations conducted at or before baseline radiography. Results: Prevalence of vertebral fracture was similar (14%) in women and men, although incidence was greater in women (24%) than men (10%). Alcohol consumption increased fracture risk in men. Multivariableadjusted ORs increased from 1.78 in men who consumed 1-3 oz of alcohol per week in middle-age years to 4.61 in those with intakes of Ն4 oz/week (trend, P ‫ס‬ 0.0099). Age, height, weight, grip strength, physical activity, metacarpal cortical area, and estrogen use (in women) had little or no influence on cumulative incidence of vertebral fracture. Results were similar when fracture was restricted to (at least) moderate severity; however, participants with moderate to severe fracture prevalent at baseline had five times the incidence of moderate to severe fracture during follow-up compared with those without moderately to severe prevalent fractures. Conclusions: Few factors in middle-aged persons, except prevalent fracture and alcohol consumption (in men), predict long-term incidence of vertebral fracture. The explanation underlying this finding is not readily apparent, however, risk factors for vertebral fracture may be more relevant to older individuals, with respect to short-term fracture risk, than to middle-aged adults in relation to long-term risk with aging.

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“…1,10,27,[39][40][41][42][43][44][45] Some of the earliest strongest evidence to support the use of QUS for discriminating between osteoporotic fractures and controls has come from large prospective studies. The first of these was published in 1990, when Porter et al measured 1 414 women over the age of 69 who were in residential accommodation.…”

Section: Fracture Discriminationmentioning

confidence: 99%

Quantitative ultrasound and bone health

Knapp¹

2009

Salud pública Méx

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Predicting vertebral deformity using bone densitometry at various skeletal sites and calcaneus ultrasound

Cited by 190 publications

References 40 publications

Factors associated with joint pain among postmenopausal women

Factors associated with joint pain among postmenopausal women

Incidence and Risk Factors for Vertebral Fracture in Women and Men: 25-Year Follow-Up Results From the Population-Based Framingham Study

Quantitative ultrasound and bone health

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