Prediction and validation of total and regional skeletal muscle mass by ultrasound in Japanese adults

Sanada, Kiyoshi; Kearns, Charles F.; Midorikawa, Taishi; Abe, Takashi

doi:10.1007/s00421-005-0061-0

Cited by 211 publications

(225 citation statements)

References 29 publications

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“…The R 2 was low and SEE value was high in the present study compared with the respective values obtained in a previous study, which used DXA to predict SM mass in children (R 2 value, 0·98; SEE, 0·565 kg, approximately 5 % of the mean measured SM mass) (2) . However, the prediction model in the present study yielded a similar R 2 value and a low SEE, compared with the corresponding values yielded by the ultrasonography-derived prediction equations for the estimation of total and regional SM mass and volume in adults (7) . Based on the estimation accuracy and the ease of obtaining measurements, ultrasonography-derived prediction in prepubertal children has a great potential as a technique for the assessment of total and regional SMV, especially in field settings.…”

Section: Discussionsupporting

confidence: 77%

“…For cadaveric studies, the CV from test-retest analyses was approximately 1 % (10) . Based on previous research that developed regression-based prediction equations for the estimation of SM mass using ultrasonography in adults (7) , the parameters of the ultrasonography-predicted equations for SMV in the present study were determined as muscle thickness in centimetres (cm) × standing height in metres(m). The following calculations were used: 'arm' = lateral forearm + anterior and posterior upper arm muscle thicknesses; 'trunk' = abdomen + subscapular muscle thicknesses; 'thigh' = anterior and posterior thigh muscle thickness; 'lower leg' = anterior and posterior lower leg muscle thickness; 'total' = 'arm' + 'trunk' + 'thigh' + 'lower leg'.…”

Section: Predicted Skeletal Muscle Volume By Ultrasonographymentioning

confidence: 99%

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Prediction and validation of total and regional skeletal muscle volume using B-mode ultrasonography in Japanese prepubertal children

et al. 2015

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Very few effective field methods are available for accurate, non-invasive estimation of skeletal muscle volume (SMV) and mass in children. We aimed to develop regression-based prediction equations for SMV, using ultrasonography, in Japanese prepubertal children, and to assess the validity of these equations. In total, 145 healthy Japanese prepubertal children aged 6-12 years were randomly divided into two groups: the model development group (sixty boys, thirty-seven girls) and the validation group (twenty-nine boys, nineteen girls). Reference data in the form of contiguous MRI with 1-cm slice thickness were obtained from the first cervical vertebra to the ankle joints. The SMV was calculated by the summation of digitised cross-sectional areas. Muscle thickness was measured using B-mode ultrasonography at nine sites in different regions. In the model development group, strong, statistically significant correlations were observed between the site-matched SMV (total, arms, trunk, thigh and lower legs) measured by MRI and the muscle thickness × height measures obtained by ultrasonography, for both boys and girls. When these SMV prediction equations were applied to the validation groups, the measured total and regional SMV were also very similar to the values predicted for boys and girls, respectively. With the exception of the trunk region in girls, the Bland-Altman analysis for the validation group did not indicate any bias for either boys or girls. These results suggest that ultrasonography-derived prediction equations for boys and girls are useful for the estimation of total and regional SMV.Key words: Skeletal muscle volume: MRI: Children: Ultrasonography: Prediction equations Although body-composition studies have been developed and refined over more than 30 years, only a limited amount of information is available on total body skeletal muscle volume (SMV) and mass in children. Studies on body composition at the organ-tissue level in children have only indicated the proportional contributions of skeletal muscle (SM) mass to body weight (1) , and the process of developing a prediction formula for SM mass is still on-going (2) . The development of SMV in children is greatly influenced by nutritional intake and the level of physical activities. Therefore, SM mass may be a very important index for the estimation of nutritional status and prediction of exercise performance during different growth stages, and is linked to the comprehensive estimation of lifestyle (3) .MRI is a precise, reliable and safe method for the measurement of total body SMV in children and adults (4,5) . However, the use of MRI for the estimation of SMV requires exclusive-use facilities and a great deal of time for image analysis. On the other hand, ultrasonography is a non-invasive and safe method for the measurement of the muscle thickness of the extremities and trunk in children (6) . Moreover, a compact-type ultrasonography machine is easily portable, which is important for use during field research and for the assessment of SMV in...

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Section: Discussionsupporting

confidence: 77%

Section: Predicted Skeletal Muscle Volume By Ultrasonographymentioning

confidence: 99%

Prediction and validation of total and regional skeletal muscle volume using B-mode ultrasonography in Japanese prepubertal children

et al. 2015

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“…Muscle cross-sectional area (CSA) and volume were determined using magnetic resonance imaging (MRI), as described previously (Abe et al, 2003;Abe et al, 2006;Sanada et al, 2006). MRI images were prepared using a General Electric Signa 1.5 Tesla scanner (Milwaukee, Wisconsin, USA).…”

Section: Upper-leg Muscle Volumementioning

confidence: 99%

Skeletal muscle size and strength are increased following walk training with restricted leg muscle blood flow: implications for training duration and frequency

Abe

Kearns

Fujita

et al. 2009

Int. J. KAATSU Ttaining Res.

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The purpose of this study was to investigate once-daily walk training with restricted leg blood flow (KAATSU) on thigh muscle size and strength. Twelve young men performed walk training: KAATSUwalk training (n=6) and control (no KAATSU-walk; n=6). Training was conducted once daily, 6 days per week, for 3 weeks. Treadmill walking (50 m/min) was performed for 5 sets of 2-min bouts interspersed with 1-min rest periods. The KAATSU-walk group wore pressure cuff belts (5 cm wide) on both legs during training, with incremental increases in external compression starting at 160 mmHg and ending at 230 mmHg. Thigh muscle volume and isometric and 1-repetition maximal (1-RM) strength were measured before and after training. In the KAATSU-walk group, quadriceps and hamstrings muscle volume increased 1.7 and 2.4% (both P<0.05), respectively, following training. One-RM leg press and leg curl increased 7.3 and 8.6% (both P<0.05), respectively, following KAATSU-walk training. Also, isometric knee extension strength (4.4%; P<0.01), but not knee flexion strength (1.7%), increased following KAATSU-walk training. There were no changes in muscle volume or strength in the control-walk group. These results confirm previous work showing that the combination of slow walk training and leg muscle blood flow restriction induces muscle hypertrophy and strength gains. However, the magnitude of change in muscle mass and strength following oncedaily KAATSU-walk training was approximately one-half that reported for twice-daily KAATSU-walk training over a 3-week period. These results in combination with previous observations lead to the conclusion that the impact of KAATSU-walk training on muscle size and strength is related to an ability to accomplish a high number of training bouts within a compressed training duration. Second, frequency-dependent muscle enlargement appears to be associated with KAATSU-walk training.

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“…Emerging literature highlights that musculoskeletal ultrasonography may be useful for assessment of muscle or lean tissue mass 10, 11. Ultrasound is a non‐invasive, readily available, and cost‐effective option that can be applied at the bedside to assess the thickness or cross‐sectional area (CSA) of specific muscle groups at predefined landmarks.…”

Section: Introductionmentioning

confidence: 99%

“…Ultrasound is a non‐invasive, readily available, and cost‐effective option that can be applied at the bedside to assess the thickness or cross‐sectional area (CSA) of specific muscle groups at predefined landmarks. Comprehensive protocols, such as the nine‐site protocol—which images anterior and posterior muscle groups in a standing posture,12 have been shown to strongly associate ( R 2 = 0.94) with whole‐body lean tissue or muscle mass 10, 13. However, few bedside viable ultrasound protocols, such as the four‐site protocol—which images the anterior muscle thickness of both quadriceps,14 have been assessed for accuracy in predicting muscle or lean tissue mass.…”

Section: Introductionmentioning

confidence: 99%

Development of a bedside viable ultrasound protocol to quantify appendicular lean tissue mass

Paris

Lafleur

Dubin

et al. 2017

J cachexia sarcopenia muscle

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BackgroundUltrasound is a non‐invasive and readily available tool that can be prospectively applied at the bedside to assess muscle mass in clinical settings. The four‐site protocol, which images two anatomical sites on each quadriceps, may be a viable bedside method, but its ability to predict musculature has not been compared against whole‐body reference methods. Our primary objectives were to (i) compare the four‐site protocol's ability to predict appendicular lean tissue mass from dual‐energy X‐ray absorptiometry; (ii) optimize the predictability of the four‐site protocol with additional anatomical muscle thicknesses and easily obtained covariates; and (iii) assess the ability of the optimized protocol to identify individuals with low lean tissue mass.MethodsThis observational cross‐sectional study recruited 96 university and community dwelling adults. Participants underwent ultrasound scans for assessment of muscle thickness and whole‐body dual‐energy X‐ray absorptiometry scans for assessment of appendicular lean tissue. Ultrasound protocols included (i) the nine‐site protocol, which images nine anterior and posterior muscle groups in supine and prone positions, and (ii) the four‐site protocol, which images two anterior sites on each quadriceps muscle group in a supine position.ResultsThe four‐site protocol was strongly associated (R 2 = 0.72) with appendicular lean tissue mass, but Bland–Altman analysis displayed wide limits of agreement (−5.67, 5.67 kg). Incorporating the anterior upper arm muscle thickness, and covariates age and sex, alongside the four‐site protocol, improved the association (R 2 = 0.91) with appendicular lean tissue and displayed narrower limits of agreement (−3.18, 3.18 kg). The optimized protocol demonstrated a strong ability to identify low lean tissue mass (area under the curve = 0.89).ConclusionsThe four‐site protocol can be improved with the addition of the anterior upper arm muscle thickness, sex, and age when predicting appendicular lean tissue mass. This optimized protocol can accurately identify low lean tissue mass, while still being easily applied at the bedside.

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Prediction and validation of total and regional skeletal muscle mass by ultrasound in Japanese adults

Cited by 211 publications

References 29 publications

Prediction and validation of total and regional skeletal muscle volume using B-mode ultrasonography in Japanese prepubertal children

Prediction and validation of total and regional skeletal muscle volume using B-mode ultrasonography in Japanese prepubertal children

Skeletal muscle size and strength are increased following walk training with restricted leg muscle blood flow: implications for training duration and frequency

Development of a bedside viable ultrasound protocol to quantify appendicular lean tissue mass

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