Prediction model for penile prosthesis implantation for erectile dysfunction management

Segal, Robert; Camper, S.B.; Ma, Larry; Burnett, Arthur L.

doi:10.1185/03007995.2014.936188

Cited by 6 publications

(2 citation statements)

References 29 publications

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“…DED is among the 2 main reasons for implantation of an implant. Segal et al (2014) developed a prediction tool based on a patient's clinical history to determine likelihood of ultimately receiving a penile prosthesis (Segal, 2014). Inclusion criteria were18 years of age with 1 year of continuous enrollment at the first diagnosis of ED.…”

Section: Penile Implantsmentioning

confidence: 99%

A Comprehensive Review of Erectile Dysfunction in Men with Diabetes

Kamenov

2014

Exp Clin Endocrinol Diabetes

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Erectile dysfunction (ED) is more common in men with diabetes (DM). Dependent on the selected population, age, DM type and duration, the prevalence of diabetic ED (DED) varies from 32 to 90%. In 12?30% of men ED is the first sign of diabetes, diagnosed later. Today men with diabetes live longer than ever, and develop more late diabetic complications. Having in mind also the global ageing of the world population all this data suggests an increasing number of men with DED in the future. The main factors playing in the complex pathogenesis of DED are diabetic neuropathy (oxidative stress, polyol pathway, advanced glycation end-products, nerve growth factor deficiency, dysfunction of protein kinase C, tissue remodeling, etc.), macrovascular arterial disease (endothelial dysfunction, abnormal collagen deposition and smooth muscle degeneration, dyslipidemia, arterial hypertension, veno-occlusive dysfunction, etc.), hypogonadism, structural remodeling of the corporeal tissue, psychogenic components and adverse drug reactions. The diagnostic process is based on the results of questionnaires, neurological, vascular (Doppler) and other more rarely used investigations. Because of the complex pathogenesis of DED diabetic men represent a ?difficult? treatment group. The difficulties are from the ?beginning?, because patients do not talk about their problem spontaneously, and doctors do not ask about it. The treatment of DED should be team work, preferably including also specialists in sexual medicine. Psychological support and counseling of the couple is necessary in most cases. The general measures include implementation of a healthier lifestyle, improved glycemic-, lipids-, and arterial pressure control, and careful re-evaluation of the concomitant medications. The specific treatment includes as first line therapy the inhibitors of phosphodiesterase type 5 (PDE-5) with lesser effectiveness compared to non-DM men. There are rare studies with selected diabetic populations and even less with head-to-head comparisons between the PDE-5 inhibitors. Men with DM have a higher prevalence of hypogonadism. Testosterone replacement therapy should be started in symptomatic men with proven hypogonadism and no contraindications. Vacuum constriction devices and intracavernous or intraurethral applications of vasoactive drugs are the second line therapy. Vascular surgery rarely comes into consideration. The penile implant is the last and effective option in men with severe DED.

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Section: Penile Implantsmentioning

confidence: 99%

A Comprehensive Review of Erectile Dysfunction in Men with Diabetes

Kamenov

2014

Exp Clin Endocrinol Diabetes

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“…A study by Tal et al found that men who had surgery as an initial treatment (versus radiotherapy), were of a younger age, were of African/American/Hispanic race, were unmarried, and were living in a geographic region other than the North-east were more likely to utilize penile implants 25 . Similarly, in a retrospective analysis of claims data from Medicare & Commercial databases of 3928 men undergoing penile prosthesis, Segal and Burnett elucidated the factors with the greatest predictive strength of penile prosthesis implantation, which included a diagnosis of prostate cancer, a diagnosis of diabetes mellitus and previous treatment with first-line ED therapy 56 .…”

Section: Predictors Of Requiring a Penile Prosthesismentioning

confidence: 99%

Inflatable penile prosthesis in the radical prostatectomy patient: a review

Bennett

Huang

2018

F1000Res

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In the population of patients with prostate cancer, survivorship has come to the forefront of continuity-of-care. In addition to urinary control, erectile function is a significant issue after radical pelvic surgery. Penile prosthesis surgery remains an excellent option for restoring erectile function to those for whom more conservative measures have failed. This review article outlines the anatomical, surgical and post-operative consideration involved in the placement of a penile prosthesis in this special patient population.

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