Prediction of Contact Angle for Pharmaceutical Solids from Their Molecular Structure

Partial least square projections to latent structures analysis (PLS) in evaluating and predicting drug release from starch acetate matrix tablets

“… The number (from 1 to 8) after the designation describes the energy levels of the target‐probe interaction from (Modified from Suihko et al, 2004) 34…”

Quantitative Correlation of Physical and Chemical Properties with Chemical Structure: Utility for Prediction

“…A more general model was developed by Suihko et al 898 for 25 structurally heterogeneous pharmaceutical materials. Molecular descriptors calculated included those derived from 3D molecular interaction fields containing attractive and repulsive forces between a chemical probe and a target molecule.…”

Biological activity of human mesenchymal stromal cells on polymeric electrospun scaffolds

“…This could be due to the relatively higher hydrophilicity of the PLA used here compared to PCL, in addition to its lower molecular weight. 29,30 PLA has been known to degrade through bulk hydrolysis of ester bonds releasing lactic acid. This may cause a drop in pH levels and increase ionic strength by releasing lactate ions that might hamper cell proliferation.…”