Knowledge Modelling and Big Data Analytics in Healthcare 2021
DOI: 10.1201/9781003142751-14
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Prediction of Disease–lncRNA Associations via Machine Learning and Big Data Approaches

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“…An integrative framework, IntNetLncSim, is presented in [26] to infer lncRNA functional similarity by modeling the information flow in an integrated network that comprises both lncRNA related transcriptional and posttranscriptional information. An approach that relies on the analysis of lncRNAs related information stored in public databases, as well as their interactions with other types of molecules is described in [17,18]. In particular, large amounts of lncRNA-miRNA interactions (LMIs) have been collected in public databases, and plenty of experimentally confirmed MDAs are available as well.…”
Section: Prediction Of Lncrnas-diseases Associationsmentioning
confidence: 99%
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“…An integrative framework, IntNetLncSim, is presented in [26] to infer lncRNA functional similarity by modeling the information flow in an integrated network that comprises both lncRNA related transcriptional and posttranscriptional information. An approach that relies on the analysis of lncRNAs related information stored in public databases, as well as their interactions with other types of molecules is described in [17,18]. In particular, large amounts of lncRNA-miRNA interactions (LMIs) have been collected in public databases, and plenty of experimentally confirmed MDAs are available as well.…”
Section: Prediction Of Lncrnas-diseases Associationsmentioning
confidence: 99%
“…The chapter is divided into three sections, each corresponding to three proposed approaches in previous chapters. In particular, most results of this PhD Thesis have been already pubblished in conferences proceedings [14,15,17,19], book chapters [18] and international journals [16]. The approaches described in the previous chapters have been implemented in Apache Spark (see Chapter 2.6.2).…”
Section: Introductionmentioning
confidence: 99%