Prediction of early acute kidney injury after trauma using prehospital systolic blood pressure and lactate levels: A prospective validation study

Abstract

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What Is Left for Real-Life Lactate Monitoring? Current Advances in Electrochemical Lactate (Bio)Sensors for Agrifood and Biomedical Applications

“…In the same vein, lactate assessment is highly appreciated in intensive care units (ICUs), where an abnormal level is a beacon of meaningful information of the current and future status of the patient. In this sense, it is possible to relate it with situations such as haemorrhagic shock, pulmonary embolism, cardiogenic shock, respiratory poisoning and renal failure, among others [ 8 , 9 , 10 , 11 , 12 , 13 ]. Moreover, alternative studies pointed out the existence of abnormal lactate concentration in cancer cells during metastases [ 14 ].…”

Role of serum lactate as prognostic marker of mortality among emergency department patients with multiple conditions: A systematic review

“…As a result, early recognition of high-risk groups for serious AKI following trauma, as well as prompt treatment, may help trauma patients have a better outcome. 33 …”

“…As a result, early recognition of high-risk groups for serious AKI following trauma, as well as prompt treatment, may help trauma patients have a better outcome. 33 In addition, the clinical value of the lactate-to-albumin ratio (LAR) as a predictor of multiple organ dysfunction syndromes (MODS) and the 30-day mortality rate were determined in patients admitted to the ED with severe trauma (Injury Severity Score ⩾ 16). The results suggest that the rise in the LAR at admission (OR = 1.618, p = 0.028) had been an independent prognosticator of MODS progress.…”

“…Nasu et al 33 Prospective review AKI Patients in the high-risk group had pre-hospital SBP of ⩽126 mmHg and lactate levels of ⩾2. Since lactate calculation in the ED is linked to clinical conditions and requirements such as multi-organ failure, injury severity, respiratory problems, hospital stay, emergency operations, mechanical ventilation, and ICU admission, therefore early (at the time of administration of hospital) and periodic (after few hours) lactate level measurements is recommended by all reported studies so that severity of patients can be determined and on basis of that therapies could be recommended for benefit of the patient.…”