Prediction of hypocalcemia after total thyroidectomy using indocyanine green angiography of parathyroid glands: A simple quantitative scoring system

Gálvez-Pastor, Silvia; Torregrosa, Nuria; Rı́os, Antonio; Febrero, Beatríz; González-Costea, R.; García-López, María Ángeles; Balsalobre, María; Pastor-Pérez, Patrícia; Moreno, Pablo; Vazquez-Rojas, José Luis; Rodrı́guez, José Manuel

doi:10.1016/j.amjsurg.2018.12.074

Cited by 33 publications

(37 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…ICGA reliably predicts the vascularization of the parathyroid glands and obviates the need for the postoperative measurement of calcium and PTH. The results of these studies are mainly concordant with regard to the concept that patients who have retained at least one well-vascularized parathyroid gland after total thyroidectomy, as demonstrated by ICG angiography (Figure 7), also exhibited normal PTH levels during the first postoperative day, thereby excluding postoperative hypoparathyroidism with a 100% positive predictive value [33,37,[39][40][41].…”

Section: Nb Pt Intervention Key Points Conclusionsupporting

confidence: 72%

See 1 more Smart Citation

Intraoperative Autofluorescence and Indocyanine Green Angiography for the Detection and Preservation of Parathyroid Glands

Demarchi

Karenovicŝ

Bédat

et al. 2020

JCM

View full text Add to dashboard Cite

Fluorescence imaging is a well-known method for both the in vivo and in vitro identification of specific cells or tissues. This imaging tool is gaining importance in the intraoperative detection and preservation of parathyroid glands during endocrine surgery owing to the intrinsic properties of parathyroid tissue. The aim of this paper is to provide an overview of the basics of the technology, its history, and the recent surgical intraoperative applications of near-infrared imaging methods. Moreover, a literature review of the utilization of fluorescence devices in thyroid surgery suggests that the use of near-infrared imaging seems to be beneficial in reducing postoperative hypoparathyroidism, which is one of the most frequent complications of thyroid surgery.

show abstract

Section: Nb Pt Intervention Key Points Conclusionsupporting

confidence: 72%

“…postoperative day, thereby excluding postoperative hypoparathyroidism with a 100% positive predictive value [33,37,[39][40][41].…”

Section: Nb Pt Intervention Key Points Conclusionmentioning

confidence: 99%

Intraoperative Autofluorescence and Indocyanine Green Angiography for the Detection and Preservation of Parathyroid Glands

Demarchi

Karenovicŝ

Bédat

et al. 2020

JCM

View full text Add to dashboard Cite

show abstract

“…We analyzed the predictive accuracy of normal postoperative parathyroid function (i.e., the diagnostic odds ratio [DOR]), plotted summary receiver operating characteristic (SROC) curves, calculated the areas under the curves (AUCs), 4,7,11–17 and determined the sensitivity of parathyroid gland identification based on ICG approaches 4,6,8,12,13,18–23 . We compared the incidence of postoperative hypoparathyroidism predicted by the ICG summed imaging score (≥2 or <2) with that derived during operations 5,7,9,11,14,24,25 …”

Section: Methodsmentioning

confidence: 99%

Indocyanine green fluorescence for parathyroid gland identification and function prediction: Systematic review and meta‐analysis

et al. 2021

View full text Add to dashboard Cite

Background To evaluate the diagnostic accuracies of indocyanine green (ICG) fluorescence for identifying parathyroid glands during surgery and predicting the postoperative function. Methods From six databases, 21 studies were finally included in the study. True‐positive, true‐negative, false‐positive, and false‐negative data were extracted for the analysis. The quality of each study was analyzed using the QUADAS‐2 tool. Results The sensitivity of ICG‐based parathyroid gland identification was 0.9380 (95% CI [0.9003, 0.9621]). The diagnostic odds ratio for ICG‐based prediction of parathyroid gland function was 54.5652 [13.2059, 225.4570]. The area under the summary receiver operating characteristic curve was 0.909. Fluorescence intensity‐based prediction presented higher diagnostic accuracy than that of score‐based prediction. The incidence of postoperative hypoparathyroidism was higher in the group with a zero ICG score compared to the high scored group. Conclusions Identification of parathyroid gland and prediction of postoperative function using ICG are valuable to patients undergoing thyroidectomy or parathyroidectomy.

show abstract

“…We would like to congratulate the authors for developing a novel scoring system to predict hypocalcemia after total thyroidectomy. 1 Indeed, their finding suggests that serial parathyroid hormone (PTH) and calcium estimation can be avoided and early discharge can be planned based on an 4-ICG score >3. However, we have some comments to make and we would like to have some of our queries answered.…”

Section: Dear Editormentioning

confidence: 99%

How important is the 4-ICG score for a thyroid surgeon?

Shekhar

Singh

Vikram

et al. 2020

The American Journal of Surgery

View full text Add to dashboard Cite

Prediction of hypocalcemia after total thyroidectomy using indocyanine green angiography of parathyroid glands: A simple quantitative scoring system

Cited by 33 publications

References 23 publications

Intraoperative Autofluorescence and Indocyanine Green Angiography for the Detection and Preservation of Parathyroid Glands

Intraoperative Autofluorescence and Indocyanine Green Angiography for the Detection and Preservation of Parathyroid Glands

Indocyanine green fluorescence for parathyroid gland identification and function prediction: Systematic review and meta‐analysis

How important is the 4-ICG score for a thyroid surgeon?

Contact Info

Product

Resources

About