Concrete is an important construction material. Its characteristics depend on the environmental conditions, construction methods, and mix factors. Working with concrete is particularly tricky in a hot climate. This study predicts the properties of concrete in hot conditions using the case study of Rawalpindi, Pakistan. In this research, variable casting temperatures, design factors, and curing conditions are investigated for their effects on concrete characteristics. For this purpose, water–cement ratio (w/c), in-situ concrete temperature (T), and curing methods of the concrete are varied, and their effects on pulse velocity (PV), compressive strength (fc), depth of water penetration (WP), and split tensile strength (ft) were studied for up to 180 days. Quadratic regression and artificial neural network (ANN) models have been formulated to forecast the properties of concrete in the current study. The results show that T, curing period, and moist curing strongly influence fc, ft, and PV, while WP is adversely affected by T and moist curing. The ANN model shows better results compared to the quadratic regression model. Furthermore, a combined ANN model of fc, ft, and PV was also developed that displayed higher accuracy than the individual ANN models. These models can help construction site engineers select the appropriate concrete parameters when concreting under hot climates to produce durable and long-lasting concrete.