Prediction of potential metastatic sites in cutaneous head and neck melanoma using lymphoscintigraphy

O’Brien, Christopher J.; Uren, Roger F.; Thompson, John F.; Howman‐Giles, Robert; Petersen‐Schaefer, Karin; Shaw, Helen M.; Quinn, Michael J.; McCarthy, William H.

doi:10.1016/s0002-9610(99)80330-4

Cited by 270 publications

(242 citation statements)

References 13 publications

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“…Furthermore, previous studies involving melanomas from all anatomic sites showed a statistically significant improvement in survival in patient with intermediate thickness melanomas (range, 1-4 mm), which suggests that some subgroups of patients may benefit from ELND 3,25,31 . Finally, despite the fact that sentinel lymph node biopsy (SLNB) has been adopted into clinical practice as reliable staging modality, there are lots of arguments against it, such as increased incidence of nodal (regional and in-transit) recurrence in sentinel lymph nodes (SLN) negative patients, possibility of false-negative results, difficult identification of SLN if they are located close to primary site, SLN found in multiple node fields in contrast to melanomas located on extremities which usually drain to only 1 field, SLN in parotid region which are often very small, may be difficult to find, and their removal may put the facial nerve at risk 8,10,12,15,16,29,36,37 . However, some authors reported that intraparotid SLN biopsy is a reliable, accurate, and safe procedure for staging cutaneous head and neck melanoma 23 .…”

Section: Discussionmentioning

confidence: 99%

Lymphatic drainage patterns of head and neck cutaneous melanoma: does primary melanoma site correlate with anatomic distribution of pathologically involved lymph nodes?

Suton¹,

Lukšić²,

Müller³

et al. 2012

International Journal of Oral and Maxillofacial Surgery

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Section: Discussionmentioning

confidence: 99%

Lymphatic drainage patterns of head and neck cutaneous melanoma: does primary melanoma site correlate with anatomic distribution of pathologically involved lymph nodes?

Suton¹,

Lukšić²,

Müller³

et al. 2012

International Journal of Oral and Maxillofacial Surgery

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“…Drainage to multiple SNs in the head and neck is common 1,24 and the nodes are often small. The draining SNs often lie very near or sometimes immediately beneath the melanoma site.…”

Section: Head and Neckmentioning

confidence: 99%

“…As we have found elsewhere, clinical prediction of lymphatic drainage in the head and neck is unreliable, and 33% of patients drain to node sites discordant with clinical prediction. 24 This is often to postauricular nodes from the skin of the face and anterior scalp. Such nodes are not usually excised during elective neck dissections for melanoma.…”

Section: Head and Neckmentioning

confidence: 99%

Lymphatic drainage of the skin

Uren

2004

Annals of Surgical Oncology

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A successful sentinel lymph node biopsy (SLNB) in melanoma patients requires an accurate map of the pattern of lymphatic drainage from the primary site. Lymphoscintigraphy (LS) can provide such a map. LS needs an understanding of lymphatic physiology, an appropriate small-particle radiocolloid, high-resolution collimators, and imaging protocols that detect all sentinel nodes (SNs). Patterns of lymphatic drainage from the skin are not clinically predictable. Unexpected drainage has been found from the skin of the back to SNs in the triangular intermuscular space (TIS) and the paraaortic, paravertebral, and retroperitoneal areas. It can also occur from the base of the neck up to nodes in the occipital or upper cervical areas or from the scalp down to nodes at the neck base, bypassing many node groups. Upper limb drainage can be to SNs above the axilla. Interval nodes not uncommonly can be SNs, especially on the trunk. Lymphatic drainage may involve SNs in multiple nodal fields, and drainage across the midline of the body is quite common. Because micrometastatic disease can be present in any SN regardless of its location, all true SNs must be biopsied. LS is an important first step to ensure this goal is achieved.

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“…Cervical lymphatic drainage is interlacing and can be watershed in nature; at least one-third of primary melanomas of the head and neck will show drainage to nodal basins outside the parotid bed and/or neck levels that are usually dissected when performing elective nodal dissections. O'Brien et al 14 demonstrated this complexity of lymphatic drainage in the head and neck by reporting a 34% discordance between the clinical prediction of lymphatic drainage and lymphoscintigraphy findings in 97 cases of head and neck cutaneous melanoma.…”

Section: First Introduced In 1992 Bymentioning

confidence: 99%

Sentinel Lymph Node Biopsy in Head and Neck Melanoma: A Review

Corsten¹,

Johnson‐Obaseki²

2014

Journal of Patient-Centered Research and Reviews

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Follow this and additional works at: https://aurora.org/jpcrr Part of the Oncology CommonsJournal of Patient-Centered Research and Reviews ( JPCRR) is a peerreviewed scientific journal whose mission is to communicate clinical and bench research findings, with the goal of improving the quality of human health, the care of the individual patient, and the care of populations. The incidence of melanoma in the United States continues to rise. Head and neck melanomas comprise approximately 20% of all primary cutaneous melanomas. Sentinel lymph node (SLN) biopsy (SLNB) has become the standard of care for staging in melanoma. It has a number of advantages, including the addition of prognostic information, accurate staging, and the potential to add completion lymph node dissection (CLND) or adjuvant therapy when indicated.

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Prediction of potential metastatic sites in cutaneous head and neck melanoma using lymphoscintigraphy

Cited by 270 publications

References 13 publications

Lymphatic drainage patterns of head and neck cutaneous melanoma: does primary melanoma site correlate with anatomic distribution of pathologically involved lymph nodes?

Lymphatic drainage patterns of head and neck cutaneous melanoma: does primary melanoma site correlate with anatomic distribution of pathologically involved lymph nodes?

Lymphatic drainage of the skin

Sentinel Lymph Node Biopsy in Head and Neck Melanoma: A Review

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