Prediction of solubility parameter from intrinsic viscosity

Han, Kyong Ho; Jeon, Gil Song; Hong, In Kwon; Lee, Seung Bum

doi:10.1016/j.jiec.2012.12.009

Cited by 39 publications

(14 citation statements)

References 25 publications

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“…The approach of the measurement of the intrinsic viscosity followed a well‐established method using an Ubbelohde viscometer (Han et al . ). The efflux times of the deionized water and the samples from the viscometer were recorded.…”

Section: Methodsmentioning

confidence: 97%

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Stable Casein‐Hydroxypropyl Cellulose Complexes at Low pH

Cheng

Cai

et al. 2016

Journal of Food Quality

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The effect of pH at acidic pH range on the stability of hydroxypropyl cellulose (HPC) and casein complexes was studied. Results suggested the occurrence of clear and transparent appearance of HPC-casein complexes at pH 2.5 and 3. After storage for 3 weeks, the complexes maintained the excellent stability, as HPC molecules attached onto the surfaces of casein micelles through electrostatic interactions with strong positive charges resulted in an interparticle electrostatic repulsion, thereby preventing aggregation. The particle size, zeta potential analysis, turbidity, the protein concentration and viscosity confirmed the hypothesis. In addition, microscopic images revealed that the polysaccharide (HPC) particles adsorbed onto the surfaces of casein micelles, and casein-HPC complexes were uniformly dispersed in the system. Moreover, the effects of the ionic strength on the stability of the complex were investigated. It was indicated that the particle size of casein-HPC complexes at low concentration (2 mM) of NaCl remained the identical level (P > 0.05), while the particle sizes significantly were increasing at the relatively higher concentrations (50 mM and 100 mM) of NaCl (P < 0.05). PRACTICAL APPLICATIONSIn this study, the casein-HPC complexes at different pH values in aqueous systems were investigated. The results illustrate that the stable casein-HPC complexes could be formed at low pH and the stability could be maintained over the duration of 3 weeks. The findings in this study would contribute to the production of acidified milk drinks in food industry.

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Section: Methodsmentioning

confidence: 97%

“…Intrinsic viscosity ( η , dL/g) can be calculated from the relative viscosity ( η r ) and specific viscosity ( η sp ) using the Huggins and Kraemer equations (Han et al . ).…”

Section: Methodsmentioning

confidence: 97%

Stable Casein‐Hydroxypropyl Cellulose Complexes at Low pH

Cheng

Cai

et al. 2016

Journal of Food Quality

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“…The use of viscosity measurements is a frequently used technique to determine the solubility parameter for polymers . In this approach, the intrinsic viscosity of the polymer of interest is determined in a number of solvents .…”

Section: Theory and Experimental Aspects Of The Solubility Parameter mentioning

confidence: 99%

Application of the solubility parameter concept to assist with oral delivery of poorly water-soluble drugs – a PEARRL review

Jankovic

Tsakiridou

Ditzinger

et al. 2019

Journal of Pharmacy and Pharmacology

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In particular, partial solubility parameters hold great promise for aiding the development of poorly soluble drug delivery systems. This is particularly true in early-stage development, where compound availability and resources are limited. The experimental determination of solubility parameters has its merits despite being rather labour-intensive because further data can be used to continuously improve in silico predictions. Such improvements will ensure that solubility parameters will also in future guide scientists in finding suitable drug formulations.

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“…The approach of the measurement of the intrinsic viscosity followed a well-established method using an Ubbelohde viscometer (Han et al, 2013). The samples were dissolved in 0.1 mol/L acetic acid with a concentration of 0.1% w/v and placed in the viscometer.…”

Section: Intrinsic Viscositymentioning

confidence: 99%

Acid‐soluble and pepsin‐soluble collagens from grass carp (Ctenopharyngodon idella) skin: a comparative study on physicochemical properties

Chen

Wang

2014

Int J of Food Sci Tech

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Summary In this study, acid‐soluble (ASC) and pepsin‐soluble (PSC) collagens with triple helical structures were successfully extracted from the skin of grass carp (Ctenopharyngodon idella) by two different extraction approaches. SDS‐PAGE pattern revealed that ASC and PSC are type I collagens with typical α1, α2 and β‐chains. In addition, the intensity of χ‐chain (trimer) in ASC was higher than that of PSC, representing the presence of the high proportion of intra‐ and intermolecular cross‐links of extracted collagens with large molecular weight using the acid method. Differential scanning calorimetry (DSC) results demonstrate that Td (69.04 °C) of ASC was higher than Td (62.20 °C) of PSC. Both ASC and PSC had the highest solubility at acidic pHs or at a low concentration of NaCl (<2%, w/v). The results of FTIR suggested the ASC and PSC maintained in the helical secondary structure at high degree.

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Prediction of solubility parameter from intrinsic viscosity

Cited by 39 publications

References 25 publications

Stable Casein‐Hydroxypropyl Cellulose Complexes at Low pH

Stable Casein‐Hydroxypropyl Cellulose Complexes at Low pH

Application of the solubility parameter concept to assist with oral delivery of poorly water-soluble drugs – a PEARRL review

Acid‐soluble and pepsin‐soluble collagens from grass carp (Ctenopharyngodon idella) skin: a comparative study on physicochemical properties

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