Prediction of tsunami of resistance to some antibiotics is not far‐fetched which used during COVID‐19 pandemic

Abstract

One of the most tragic events in recent history was the COVID‐19 outbreak, which has caused thousands of deaths. A variety of drugs were prescribed to improve the condition of patients, including antiparasitic, antiviral, antibiotics, and anti‐inflammatory medicines. It must be understood, however, that COVID‐19 is like a tip of an iceberg on the ocean, and the consequences of overuse of antibiotics are like the body of a mountain under water whose greatness has not yet been determined for humanity, and additional study is needed to understand them. History of the war between microbes and antimicrobial agents has shown that microbes are intelligent organisms that win over antimicrobial agents over time through many acquired or inherent mechanisms. The key terms containing “COVID‐19,” “Severe acute respiratory syndrome coronavirus‐2,” “SARS‐CoV2,” “Antibiotic Resistance,” “Coronavirus,” “Pandemic,” “Antibiotics,” and “Antimicrobial Resistance” were used for searching in PubMed, Scopus, and Google Scholar databases. The COVID‐19 pandemic has resulted in an increased prescription of antibiotics. Infections caused by secondary or co‐bacterial infections or beneficial bacteria in the body can be increased as a result of this amount of antibiotic prescription and exposure to antibiotics. Antibiotic resistance will likely pose a major problem in the future, especially for last resort antibiotics. In order to address the antibiotic resistance crisis, it is imperative that researchers, farmers, veterinarians, physicians, public and policymakers, pharmacists, other health and environmental professionals, and others collaborate during and beyond this pandemic.

Pre- and Post-COVID-19 Antimicrobial Resistance Pattern of Pathogens in an Intensive Care Unit

“…The inappropriate use of antibiotics in viral illnesses and in the absence of bacterial co-infection may be an enabling factor for the selection of multidrug-resistant strains. The overuse of antibiotics, especially those most used to treat secondary bacterial infections in COVID-19 patients (amoxicillin, azithromycin, and cephalosporins), has contributed to the development of new, antibiotic-resistant bacterial strains against them [ 10 , 11 , 12 , 13 , 14 ].…”