Prediction parameters of left ventricular diastolic dysfunction improvement in patients after acute coronary syndrome

Bjelobrk, Marija; Miljković, Tatjana; Ilić, Aleksandra; Milovančev, Aleksandra; Tadić, Snežana; Bjelić, Snežana; Dabović, Dragana; Čanković, Milenko; Ivanović, Vladimir; Preveden, Andrej; Popović, Dragana

doi:10.1080/17843286.2022.2114678

Cited by 1 publication

(1 citation statement)

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“…This positive effect is achieved mainly through the stimulation of NO release and endothelial responsiveness to vasodilator activity [7]. Previous studies demonstrated that exercise training provides beneficial effects and is capable of improving endothelial function in patients with arterial hypertension, coronary artery disease, heart failure and peripheral artery disease [9,[23][24][25]. More specifically, a study by Payvandi et al [8] showed higher values of FMD in the brachial artery among individuals with peripheral artery disease who have regular physical activity during their daily life, even without a professionally supervised exercise programme.…”

Section: Discussionmentioning

confidence: 99%

Influence of physical activity on endothelial function in people living with HIV

Preveden,

Čolović,

Garipi

et al. 2023

HIV Medicine

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IntroductionDecreased physical activity is a major cardiovascular risk factor that is particularly pronounced in people living with HIV (PLHIV), who are more susceptible to endothelial dysfunction and accelerated atherosclerosis than the general population due to multiple mechanisms. The aim of the present study was to analyse whether regular physical activity is capable of improving endothelial function measured by flow‐mediated dilatation (FMD) in PLHIV.MethodsWe performed FMD measurement in 38 PLHIV, along with the assessment of their regular physical activity level using the International Physical Activity Questionnaire (IPAQ).ResultsFlow‐mediated dilatation results in PLHIV were 0.31 ± 0.06 mm and 7.34% ± 1.41% for absolute and relative FMD, respectively. IPAQ results showed that the average weekly level of physical activity was 3631.1 ± 1526.7 MET‐min/week, whereas the average daily sitting time was 287.3 ± 102.7 min/day. Predictors jointly accounted for 48% (adjusted value 42%) of FMD variance. Bootstrapped confidence levels revealed that physical activity had a statistically significant effect on the outcome [beta = 0.517, 2.5% confidence interval (CI) = 0.205, 97.5% CI = 0.752].ConclusionPhysical activity represents a widely available and uncostly tool that is capable of improving endothelial function and overall cardiovascular health in PLHIV.

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