2015
DOI: 10.1002/sam.11261
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Prediction using hierarchical data: Applications for automated detection of cervical cancer

Abstract: Although the Papanicolaou smear has been successful in decreasing cervical cancer incidence in the developed world, there exist many challenges for implementation in the developing world. Quantitative cytology, a semi-automated method that quantifies cellular image features, is a promising screening test candidate. The nested structure of its data (measurements of multiple cells within a patient) provides challenges to the usual classification problem. Here we perform a comparative study of three main approach… Show more

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Cited by 14 publications
(5 citation statements)
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“…Furthermore, by using the nested structure of its data to extract patient-level features from the cell-level data, utilizing a statistical model that takes advantage of the hierarchical data structure, and classifying the cellular level [37], it executed comparative research on three primary methods for solving problems. With an estimated 61% sensitivity and 89% specificity on independent data, the optimal method was to classify at the cellular level and count the number of cells with a posterior probability larger than a threshold value.…”
Section: -2015mentioning
confidence: 99%
“…Furthermore, by using the nested structure of its data to extract patient-level features from the cell-level data, utilizing a statistical model that takes advantage of the hierarchical data structure, and classifying the cellular level [37], it executed comparative research on three primary methods for solving problems. With an estimated 61% sensitivity and 89% specificity on independent data, the optimal method was to classify at the cellular level and count the number of cells with a posterior probability larger than a threshold value.…”
Section: -2015mentioning
confidence: 99%
“…One of the studies by Ho et al [15] used a logistic regression model and compared the results with Chi-square Automatic Interaction Detector (CHAID) model on the dataset with 12 attributes and 710 samples. Initially, logistic regression is built in an assumption that it takes a major position in predicting or classifying the clinical outcomes.…”
Section: Literature Studymentioning
confidence: 99%
“…The methods and techniques have been used for www.ijacsa.thesai.org screening of cervical cancer are limited to small number of parameters. The available literature for screening of cervical cancer explores mainly Papanicolaou (Pap) smear test [17], hormonal status, FIGO stage [18] and cervical intraepithelial neoplasia (CIN) [19] but only single parameter was used for screening prediction of cervical cancer. The available data mining techniques using large number of parameters [20][21][22][23] were not given effective results.…”
Section: Introductionmentioning
confidence: 99%