Predictive Effect of Preoperative Anemia on Long-Term Survival Outcomes with Non-Muscle Invasive Bladder Cancer

Çelik, Orçun; Akand, Murat; Keskın, Mehmet; Ekin, Rahmi Gökhan; Yoldaş, Mehmet; İlbey, Yusuf Özlem

doi:10.7314/apjcp.2016.17.4.1755

Cited by 9 publications

(5 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Compared to anemic values, a normal preoperative hemoglobin value was shown to significantly reduce the likelihood of transfusion after laparoscopic colorectal resection (HR 0.547, 95% CI 0.468-0.637). 36 Finally, preoperative anemia is independently associated with worse oncologic outcomes in patients with urologic, gastric, colorectal or mesenchymal cancer, with decreased disease-free survival, 37,38 cancer-specific survival 39,40 and overall survival, 39,[41][42][43] and increased rates of cancer recurrence. 40,44 2.…”

Section: Preoperative Anemia Is Associated With Adverse Sur-mentioning

confidence: 99%

Clinical practice guideline: evidence, recommendations and algorithm for the preoperative optimization of anemia, hyperglycemia and smoking

Greenberg

Zwiep

Sadek

et al. 2021

cjs

View full text Add to dashboard Cite

Clinical practice guideline: evidence, recommendations and algorithm for the preoperative optimization of anemia, hyperglycemia and smoking F or most of the 20th century, the focus of research in surgery was improvements in intraoperative technique, which led to major technical paradigm shifts exemplified by the evolution of transurethral resection of the prostate, 1 laparoscopic cholecystectomy, 2 endovascular aneurysm repair 3 and total mesorectal excision for rectal cancer, 4 among many others. The late 1990s and early 2000s marked a shift in surgical research toward the evidencebased management of patients in the perioperative period, beginning with the Enhanced Recovery After Surgery Group's systematic review of patients undergoing colorectal surgery. 5 That publication introduced a new paradigm focused on the impact that standardized perioperative care could have on patient outcomes such as length of stay, postoperative pain and overall complication rates. 6,7 Although a large body of literature now exists to help guide the intraoperative and perioperative management of surgical patients, our working group believes that the preoperative period, which we define as the 8 weeks

show abstract

Section: Preoperative Anemia Is Associated With Adverse Sur-mentioning

confidence: 99%

Clinical practice guideline: evidence, recommendations and algorithm for the preoperative optimization of anemia, hyperglycemia and smoking

Greenberg

Zwiep

Sadek

et al. 2021

cjs

View full text Add to dashboard Cite

show abstract

“…Just as the previous studies showed, a retrospective study conducted by Zhang showed that hemoglobin is an independent risk factor affecting the prognosis of patients with MIBC 21 . Similarly, Celik found that preoperative anemia status of BC patients is associated with decreased OS, but not with cancer-specific survival 22 . Chen revealed that BC patients with anemic are likely to have a shorter recurrence-free survival (RFS) and OS than non-anemic patients 23 .…”

Section: Discussionmentioning

confidence: 95%

Relationship between testosterone and male bladder cancer

Tan

Gao

Yuan

et al. 2023

Sci Rep

View full text Add to dashboard Cite

Researches had proven that the occurrence of bladder cancer (BC) is much higher in men than those in women, which induced us to explore whether androgen plays a role in BC. A total of 147 patients who were diagnosed with primary BC by histopathological biopsy were included. Meanwhile 154 non-tumor patients were matched as the control group. The continuous variables were expressed as median (interquartile range, IQR) and compared by Mann–Whitney U test, for the reason that the data were not matched the requirementsthe of normal test. A Chi-square test was used to compare the categorical variables, which were expressed as frequency (percentage). Meanwhile univariate and multivariate logistic regression was done to further evaluating the potential independent factor of BC. P < 0.05 was considered statistically significant. Univariate multivariate analyse showed significant difference between two groups in hemoglobin (OR 0.979, 95% CI 0.968–0.991, P < 0.001), hypertension (OR 3.026, 95% CI 1.731–5.288, P < 0.001), diabetes (OR 4.294, 95% CI 1.887–9.771, P = 0.001) and smoking (OR 1.729, 95% CI 1.096–2.729, P = 0.019). Furthermore, multivariate logistic regression analysis was conducted to eliminate the interference of confounding factors, which showed that testosterone seems to be great correlated with the BC (OR 1.002, 95% CI 1.000–1.003, P = 0.017). Similar results were also found in hemoglobin (OR 0.981, 95% CI 0.968–0.993, P = 0.002), hypertension (OR 2.780, 95% CI 1.509–5.120, P = 0.001), diabetes (OR 3.313 95% CI 1.373–7.991, P = 0.008) and smoking (OR 1.938, 95% CI 1.184–3.174, P = 0.009). As a conclusion, our study showed that there was significant correlation between serum total testosterone levels and the occurrence of BC, similar results were shown in hemoglobin, hypertension, diabetes and smoking.

show abstract

“…Orcun et al . evaluated the prognostic role of preoperative anemia on long-term survival outcomes in NMIBC 25 . They found that 118 (36.9%) patients with anemia showed decreased overall survival.…”

Section: Discussionmentioning

confidence: 99%

Prognostic value of impaired estimated glomerular filtration rate in intravesical BCG-treated non–muscle-invasive bladder cancer patients

Tae

Kim

Kang

et al. 2017

Sci Rep

View full text Add to dashboard Cite

To evaluate the influence of patient-associated parameters and comorbities, with a special focus on renal function after intravesical adjuvant bacillus Calmette-Gue´rin (BCG) immunotherapy in patients with non–muscle-invasive bladder cancer (NMIBC). We retrospectively reviewed the medical records of patients treated from October, 1991 to December, 2013 at Seoul National University who were diagnosed with NMIBC and treated with intravesical BCG. A total of 344 patients who were diagnosed with NMIBC and treated with intravesical BCG were enrolled in this study. Tumor recurrence was observed in 171 patients (49.3%); progression to higher pT category or grade was found in 68 patients (15.1%). Multivariate analysis demonstrated that recurrent tumors and the presence of multiple tumors increased the risk of recurrence. However, other factors also appeared to predict recurrence, such as impaired renal function (<60 ml/min), which was associated with recurrence in univariate and multivariate analyses (HR 1.879 p = 0.008). It is worthy of notice that impaired renal function was an independent predictor of tumor recurrence after BCG instillation in multivariate analysis. Therefore, we should consider not only the clinical or pathologic findings of a tumor but also renal function during decision-making for additional therapy.

show abstract

Predictive Effect of Preoperative Anemia on Long-Term Survival Outcomes with Non-Muscle Invasive Bladder Cancer

Cited by 9 publications

References 19 publications

Clinical practice guideline: evidence, recommendations and algorithm for the preoperative optimization of anemia, hyperglycemia and smoking

Clinical practice guideline: evidence, recommendations and algorithm for the preoperative optimization of anemia, hyperglycemia and smoking

Relationship between testosterone and male bladder cancer

Prognostic value of impaired estimated glomerular filtration rate in intravesical BCG-treated non–muscle-invasive bladder cancer patients

Contact Info

Product

Resources

About