2006
DOI: 10.1097/01.tp.0000209602.54351.a6
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Predictive Factors for Anemia Six and Twelve Months After Orthotopic Liver Transplantation

Abstract: Anemia is highly prevalent within the first year post-OLT. This deserves further investigation and appropriate treatment.

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Cited by 7 publications
(8 citation statements)
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“…Splenectomy is known to be effective and safe in combination with PEG‐IFN/RBV therapy for thrombocytopenic patients with HCV‐related cirrhosis, 13–15 but its efficacy in alleviating anemia is yet to be demonstrated. In the guidelines for the treatment of chronic hepatitis and cirrhosis due to HCV in Japan, 16 a splenectomy is recommended for patients with a platelet count less than 50 000/mm 3 . Kishi et al 17 .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Splenectomy is known to be effective and safe in combination with PEG‐IFN/RBV therapy for thrombocytopenic patients with HCV‐related cirrhosis, 13–15 but its efficacy in alleviating anemia is yet to be demonstrated. In the guidelines for the treatment of chronic hepatitis and cirrhosis due to HCV in Japan, 16 a splenectomy is recommended for patients with a platelet count less than 50 000/mm 3 . Kishi et al 17 .…”
Section: Discussionmentioning
confidence: 99%
“…Of these problems, anemia is a serious matter, especially for Japanese patients, as erythropoietin replacement therapies are not covered by public medical insurance and are seldom performed. Furthermore, the incidence of anemia after LT is as high as 50%, even without anti‐HCV therapy 3 . PEG‐IFN/RBV therapy for recurrent hepatitis C after LT has been reported to cause anemia in no less than 71% of recipients 4 .…”
Section: Introductionmentioning
confidence: 99%
“…Some of these risk factors for chronic anemia, such as poor renal function and medication toxicity, are well described in the general pediatric and adult transplant literature (3–7, 10, 11, 15). Others, such as leukopenia and age, represent novel risk factors not previously identified.…”
Section: Discussionmentioning
confidence: 99%
“…There exist fewer studies that describe the prevalence of chronic anemia and its associated risk factors in recipients of liver transplants. In a recent adult cohort, the prevalence of anemia, defined by World Health Organization criteria of hemoglobin <13 g/dL for men and <12 g/dL for women, reached 50% and 53% at 6 and 12 months post–liver transplant, respectively (10). Data regarding chronic anemia in pediatric recipients of liver transplants are limited as well, although the reported prevalence ranges from 20% to 28% in recent small, retrospective studies (11, 12).…”
mentioning
confidence: 99%
“…Guitard et al observed that a daily dosage of steroids < 0.3 mg/kg at one month after transplantation was strongly associated with anemia at six and 12 months after orthotopic liver transplantation. 47 More recently, Jones et al found that prednisone was independently predictive of decreased hemoglobin in a cohort of 530 kidney allograft recipients, but they did not discuss or justify this observation. 48 …”
Section: Immunosuppression Without Steroidsmentioning
confidence: 99%