Predictive factors for loco-regional (LR) failures after intensity modulated radiotherapy (IMRT) for head and neck (HN) cancers

Feng, Mingli; Jabbari, Siavash; Lin, Alan; Schipper, Matthew; Dawson, Leonard; Tsien, Christina; EISBRUCH, A

doi:10.1016/s0360-3016(04)01752-3

Cited by 1 publication

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“…Since then, many institutions have reported their clinical experience with this new treatment technique [11][12][13][14][15][16][17][18][19][20][21] (Table 1). Despite the broad variability in patient population (tumor location, disease stage, and definitive or postoperative irradiation) and treatment technique (dose, fractionation scheme, IMRT delivery technique), these publications demonstrate the feasibility of parotid sparing IMRT for treating head and neck cancer.…”

Section: Clinical Experience With Imrtmentioning

confidence: 99%

Clinical application of intensity-modulated radiotherapy for head and neck cancer

et al. 2008

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Intensity-modulated radiotherapy (IMRT) is a modern treatment technique that allows one to shape the dose to the target volume and to reduce the dose delivered to healthy tissue. Over the last decade, IMRT has been implemented for head and neck cancer treatment, with the aim of reducing the dose delivered to the parotid glands and improving the dose coverage of complex target volumes located close to critical structures. The potential benefits of IMRT in terms of salivary function preservation and better local control have contributed to the rapid diffusion of this new technology. However, it should not be overlooked that IMRT is a novel treatment technique and that its clinical application represents a paradigm shift in the practice of radiation oncology. The purpose of this article is to review the clinical experience with IMRT for head and neck cancer treatment and to discuss some important issues related to its implementation.

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