Predictive factors of cough after uniportal video-assisted thoracoscopic pulmonary resection

Pan, Liu-Ying; Peng, Liping; Xu, Chun; Ding, Cheng; Wang, Wenyi; Zhu, Xinyu; Chang, Li

doi:10.21037/jtd-20-2652

Cited by 18 publications

(21 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this experiment, double lumen endotracheal intubation under general anesthesia was used to eliminate the bias caused by using different anesthesia methods. Our findings confirmed that the longer the anesthesia was maintained, the more prone the patient was to chronic cough after operation, which was consistent with previous studies ( 31 , 32 ).…”

Section: Discussionsupporting

confidence: 93%

Effects of Preserving the Pulmonary Vagus Nerve Branches on Cough After Pneumonectomy During Video-Assisted Thoracic Surgery

Wang

et al. 2022

Front. Oncol.

View full text Add to dashboard Cite

BackgroundCough is one of the most common complications of early-stage non-small cell lung cancer (NSCLC) after video-assisted thoracoscopic surgery (VATS). The vagus nerve plays an important role in pulmonary inflammation and the cough reflex. In this study, we attempted to reduce the incidence of postoperative chronic cough and other complications by preserving the pulmonary vagus nerve branches.Patients and MethodsThis study was a randomized controlled double-blinded trial of subjects and observers. A total of 158 NSCLC patients were enrolled. We randomly assigned 79 patients to Group A (pulmonary branch of vagus nerve preservation group) and 79 cases to Group B (conventional surgical treatment group). In the final analysis, 72 patients from Group A and 69 patients from Group B were included. The main outcome measure of the study was the occurrence of CAP or other postoperative complications within five weeks. This trial was registered with ClinicalTrials.gov (number NCT03921828).ResultsThere was no significant difference in preoperative general clinical data between the two groups. No death during the perioperative period occurred in either of the two groups. There was no significant difference between the two groups in operation time, intraoperative bleeding, number of lymph nodes sent for examination, number of cases transferred to ICU after operation, postoperative catheterization time, or postoperative hospital stay (P>0.05). There was no significant difference in other pulmonary and cardiovascular complications between the two groups, including pulmonary infection (2.78% vs. 8.70%, P = 0.129), atelectasis (1.39% vs. 0%, P = 0.326), pleural effusion (2.78% vs. 1.45%, P = 0.585), persistent pulmonary leakage (2.78% vs. 2.90%, P = 0.965), arrhythmia (2.78% vs. 1.45%, P = 0.585), and heart failure (0% vs. 1.45%, P = 0.305). The incidence of CAP in Group A was significantly lower than that in Group B (13.89% vs. 30.43%, P = 0.018). The LCQ-MC scores in Group A were significantly higher than those in Group B at two and five weeks after operation (P<0.05). Univariate and multivariate analysis showed that the risk factors for postoperative CAP were surgical side (right lung), surgical lung lobe (upper lobe), preservation of pulmonary branch of the vagus nerve during operation, and duration of anesthesia.ConclusionsPreserving the pulmonary vagus nerve branches during VATS in patients with stage IA1-2 NSCLC can reduce the incidence of postoperative CAP.

show abstract

Section: Discussionsupporting

confidence: 93%

Effects of Preserving the Pulmonary Vagus Nerve Branches on Cough After Pneumonectomy During Video-Assisted Thoracic Surgery

Wang

et al. 2022

Front. Oncol.

View full text Add to dashboard Cite

show abstract

“…Among them, systematic lymph node dissection, especially the dissection of subcarinal lymph nodes, is one of the most important risk factors. 7 In a previous study, 8 we also confirmed that subcarinal lymph node dissection is an independent risk factor for CAP. Nevertheless, our study has not further elucidated the mechanism of the aggravation of postoperative cough by subcarinal lymph node dissection.…”

Section: Introductionsupporting

confidence: 83%

Effects of preserving the bronchial artery on cough after thoracoscopic lobectomy

Pan

Zhou

et al. 2021

Thoracic Cancer

Self Cite

View full text Add to dashboard Cite

Background: The purpose of this prospective study was to explore the influence of both preoperative three-dimensional (3D) reconstruction and intraoperative preservation of the bronchial artery (BA) on postoperative cough after thoracoscopic lobectomy. Methods: A total of 60 patients who had received a combination of thoracoscopic lobectomy and systematic lymph node dissection were included in this study. They were divided into two groups, namely the BA preservation group (Group A), and conventional surgical treatment group (Group B). In group A, we used Exoview software for 3D reconstruction of the BA before the operation and the BA was preserved during the operation. 3D reconstruction of the BA was not performed before surgery in group B. The incidence of postoperative cough, the Mandarin Chinese version of the Leicester cough questionnaire (LCQ-MC), physiological, psychological and social dimensions and total score of the two groups were compared and analyzed. Results: The scores and total scores of LCQ-MC in group B were lower than those in group A one and two months after surgery. There were significant differences between the two groups in physiological and psychological dimensions and total scores (p < 0.05), but there was no significant difference in social dimension between the two groups (p > 0.05). The incidence of postoperative cough in group A (16.7%) was lower than that in group B (30%), while the difference was not statistically significant (p = 0.222). Conclusions: Preoperative 3D reconstruction and intraoperative preservation of the BA can reduce the severity of postoperative cough.

show abstract

“…The often complex perioperative factors when performing pulmonary resection prevent researchers from addressing the issue of PIC. A range of reasons are assumed to account for this, including airway infection, asthma, end-bronchial sutures, lymph node dissection, gastrointestinal reflux, postoperative physical deconditioning, and bronchial kink (3,4). Following right upper lobectomy (RUL), the remaining trachea and lungs need to adapt to the new conditions.…”

Section: Introductionmentioning

confidence: 99%

Bronchial morphological changes are associated with postoperative intractable cough after right upper lobectomy in lung cancer patients

Lu¹,

Min²,

Biao³

et al. 2022

Quant Imaging Med Surg

View full text Add to dashboard Cite

Background: To date, postoperative intractable cough (PIC) has not received adequate attention, and the complex perioperative factors when performing pulmonary resection often prevent researchers from addressing this issue. This study aimed to investigate the clinicopathological and radiographic indicators related to PIC in lung cancer patients.Methods: In all, 112 patients who had had right upper lobectomy for primary lung cancer from January 2019 to December 2020 were retrospectively reviewed. We collected data via the electronic medical database of our department. Bronchial morphological features were investigated comprehensively via threedimensional chest computer tomography reconstruction images.Results: During outpatient follow-up visits, 41 (36.6%) patients complained about persistent dry cough after surgery. Compared with the non-cough group, patients in the refractory cough group showed significant differences in smoking history, right upper lobe stump length, changes of right bronchus intermedius (RBI) diameter, changes of right lower lobe (RLL) basal bronchus diameter, changes of RBI/ RLL bronchial angle, and bronchial kink. However, according to multivariable regression analysis, stump length, bronchial kink, and diameter change of the right lower lobe basal bronchus were independently associated with postoperative refractory cough. A nebulization drug was prescribed for the 41 patients diagnosed with PIC, and 33 (80.5%) patients had improved by the next visit.Conclusions: After right upper lobectomy, the morphology of the remaining bronchial tree in the residual lung changed significantly. The bronchial morphological alterations were independent risk factors for PIC.

show abstract

Predictive factors of cough after uniportal video-assisted thoracoscopic pulmonary resection

Cited by 18 publications

References 40 publications

Effects of Preserving the Pulmonary Vagus Nerve Branches on Cough After Pneumonectomy During Video-Assisted Thoracic Surgery

Effects of Preserving the Pulmonary Vagus Nerve Branches on Cough After Pneumonectomy During Video-Assisted Thoracic Surgery

Effects of preserving the bronchial artery on cough after thoracoscopic lobectomy

Bronchial morphological changes are associated with postoperative intractable cough after right upper lobectomy in lung cancer patients

Contact Info

Product

Resources

About