Predictive indices of successful cardiac resuscitation after prolonged arrest and experimental cardiopulmonary resuscitation

Niemann, James T.; Criley, J. Michael; Rosborough, John P.; Niskanen, Robert A.; Alferness, Clif A.

doi:10.1016/s0196-0644(85)80774-5

Cited by 219 publications

(57 citation statements)

References 18 publications

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“…223,224 At low doses, the ␤-adrenergic effects may predominate, leading to decreased systemic vascular resistance; in the doses used during cardiac arrest, the vasoconstrictive ␣-effects predominate.…”

Section: Epinephrinementioning

confidence: 99%

Part 14: Pediatric Advanced Life Support

Kleinman¹,

Chameides²,

Schexnayder³

et al. 2010

Circulation

915

304

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Section: Epinephrinementioning

confidence: 99%

Part 14: Pediatric Advanced Life Support

Kleinman¹,

Chameides²,

Schexnayder³

et al. 2010

Circulation

915

304

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“…(2) Different critical threshold levels for CorPP predictive of outcome have been identified in various cardiac arrest models, corresponding to 20 mm Hg in dogs, 15 mm Hg in humans, and 10 mm Hg in pigs. (2,23,24) In order to increase CorPP above these resuscitability thresholds, administration of exogenous vasopressors is often necessary.…”

Section: Discussionmentioning

confidence: 99%

Terlipressin/adrenaline is better than adrenaline alone in a porcine model of prolonged ventricular fibrillationA randomized controlled study

2012

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12 ± 4, 11 ± 6, and 10 ± 5 mmHg in the terlipressin group A; and 6 ± 4, 1 ± 5, <0.001, and <0.001). CPP measured at the same times was 23 ± 7, 20 ± 7, and 23 ± 7 mmHg in group A; and 13 ± 7, 6 ± 5, and 6 ± 7 mmHg in group B (P=0.01, <0.001, and <0.001). Conclusion. The study showed that a single dose of terlipressin, when added to adrenaline, was effective for achievement of higher vital organ perfusion pressures compared to adrenaline alone.

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“…Fig. 2 The peak diastolic method, as described by Niemann et al 1985 andFries et al 2006 Fig . 3 The mid-diastolic method, as described by Niemann et al 1982, Sanders et al 1985, and Tang et al 1997 Fig .…”

Section: Methodsmentioning

confidence: 99%

“…6 The diastolic mean method, as described by Fenely et al 1988, Cohen et al 1992, and Wik et al 1996 Fig . 7 The true mean method, as described by Geddes et al 2007, Niemann et al 1985, Babbs 2006, and Jung et al 2006 Results Table 1 displays the CPP for the normally beating heart immediately before the episode of VF and the CPP provided by standard CPR (performed according to the 2005 AHA guidelines) during VF, as calculated by each of the CPP methods.…”

Section: Methodsmentioning

confidence: 99%

“…Table 2 compares the ratio of calculated CPP to true mean CPP for each calculation method. Using a technique similar to the CPI method of Geddes et al 2007, Niemann et al 1985 recorded CPP by continuously subtracting right atrial from aortic pressure throughout the entire CPR cycle. Applying the method of Niemann et al (1985) to this dataset, and then averaging the resulting CPP over the time interval (similar to the true mean method) provides a CPP of 11 mmHg.…”

Section: Methodsmentioning

confidence: 99%

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Methods for Calculating Coronary Perfusion Pressure During CPR

et al. 2009

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Coronary perfusion pressure (CPP) is a major indicator of the effectiveness of cardiopulmonary resuscitation in human and animal research studies; however methods for calculating CPP differ among research groups. Here we compare the 6 published methods for calculating CPP using the same data set of aortic (Ao) and right atrial (RA) blood pressures. CPP was computed using each of the 6 calculation methods in an anesthetized pig model, instrumented with catheters with Cobe pressure transducers. Aortic and right atrial pressures were recorded continuously during electrically induced ventricular fibrillation and standard CPR. CPP calculated from the same raw data set by the 6 calculation methods ranged from -1 (signifying retrograde blood flow) to 26 mmHg (mean ± SD of 15 ± 11 mmHg). The CPP achieved by standard closed chest CPR is typically reported as 10-20 mmHg. Within a single study the CPP values may be comparable; however, the CPP values for different studies may not be reliable indicators of the relative efficacies of different CPR methods. Electronically derived, true mean coronary perfusion pressure is arguably the gold standard metric for representing coronary perfusion pressure.

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Predictive indices of successful cardiac resuscitation after prolonged arrest and experimental cardiopulmonary resuscitation

Cited by 219 publications

References 18 publications

Part 14: Pediatric Advanced Life Support

Part 14: Pediatric Advanced Life Support

Terlipressin/adrenaline is better than adrenaline alone in a porcine model of prolonged ventricular fibrillationA randomized controlled study

Methods for Calculating Coronary Perfusion Pressure During CPR

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