Predictive Power of Serial Neonatal Therapeutic Intervention Scoring System Scores for Short-term Mortality in Very-low-birth-weight Infants

Wu, Pei-Ling; Lee, Wei-Te; Lee, Pei-Lun; Chen, Hsiu-Lin

doi:10.1016/j.pedneo.2014.06.005

Cited by 14 publications

(23 citation statements)

References 16 publications

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“…23 Our recently published study demonstrated that the NTISS score at 48 hours can effectively predict mortality in very low birth weight infants. 24 Hsu et al 25 reported bloodstream infections in 793 neonates, and they found that NTISS scores !23 had a higher risk (OR: 6.61, 95% CI: 2.40e26.47) of treatment failure in neonatal bacteremia. In the current study, the NTISS score in the LBW infants with VAP was significantly higher than in those without VAP.…”

Section: Discussionmentioning

confidence: 99%

Ventilator-Associated Pneumonia in Low Birth Weight Neonates at a Neonatal Intensive Care Unit: A Retrospective Observational Study

Lee

Chen

2017

Pediatrics & Neonatology

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Section: Discussionmentioning

confidence: 99%

Ventilator-Associated Pneumonia in Low Birth Weight Neonates at a Neonatal Intensive Care Unit: A Retrospective Observational Study

Lee

Chen

2017

Pediatrics & Neonatology

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“…Regarding the NTISS, the mean value found (19.9) during the first day of hospitalization did not vary widely than a study carried out to evaluate the severity of critically ill newborns in Ukraine (22.4), as well as compared to other types of studies, showing similarity in the severity and use of interventions in neonatal care in different localities, such as Londrina (17.2), performed with 81 newborns; in Mato Grosso do Sul (18), with 83 newborns; in Mexico (20.4), with 505 newborns; and Taiwan (20.3) with 172 newborns (6,(11)(12)(13)(14) .…”

Section: Discussionmentioning

confidence: 91%

Identificação da gravidade e do uso de intervenções em recém-nascidos com asfixia perinatal

Carneiro¹,

Mendes²,

Gomes³

et al. 2018

Rev Rene

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Objetivo: identificar a gravidade e o uso de intervenções em recém-nascidos com asfixia perinatal. Métodos: estudo documental, realizado com 48 prontuários de recém-nascidos com asfixia perinatal em Unidade de Terapia Intensiva Neonatal, baseado no sistema de escore para intervenção terapêutica neonatal. Dados analisados por meio de estatística descritiva e inferencial. Resultados: os recém-nascidos avaliados apresentaram complicações como infecção neonatal presumida (63,2%), insuficiência respiratória (59,1%), sepse (38,7%) e convulsão (39,7%). Durante a internação, 35,4% foram a óbito. As intervenções mais utilizadas foram transporte e sinais vitais (100,0%), ambiente termorregulado (97,9%), ventilação mecânica invasiva (91,6%), antibióticos (77,0%), intubação (75,0%), flebotomia (72,9%) e cateter venoso central (68,7%). Conclusão: a média de pontuação do escore Neonatal Therapeutic Intervention Scoring System foi de 19,9, sendo verificadas médias estatisticamente diferentes entre as categorias das variáveis Duração da internação, Desfecho clínico e Escolaridade da mãe.

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“…Gray and colleagues developed the NTISS while Shah et al developed a score using selected variables derived from the NTISS [ 19 , 32 ]. Seven of the articles reporting external application to new populations used the NTISS [ 33 – 39 ]. One study used a therapeutic score originally developed for adults, the therapeutic intervention scoring system (TISS) [ 40 ].…”

Section: Resultsmentioning

confidence: 99%

“… Oygur,2012 [ 38 ] + - + + + - Shah,2015 [ 32 ] + - + + ? + Wu,2015 [ 39 ] + - + + + ? + Limitation present - No limitation ?…”

Section: Resultsmentioning

confidence: 99%

A systematic review of neonatal treatment intensity scores and their potential application in low-resource setting hospitals for predicting mortality, morbidity and estimating resource use

et al. 2017

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BackgroundTreatment intensity scores can predict mortality and estimate resource use. They may therefore be of interest for essential neonatal care in low resource settings where neonatal mortality remains high. We sought to systematically review neonatal treatment intensity scores to (1) assess the level of evidence on predictive performance in predicting clinical outcomes and estimating resource utilisation and (2) assess the applicability of the identified models to decision making for neonatal care in low resource settings.MethodsWe conducted a systematic search of PubMed, EMBASE (OVID), CINAHL, Global Health Library (Global index, WHO) and Google Scholar to identify studies published up until 21 December 2016. Included were all articles that used treatments as predictors in neonatal models. Individual studies were appraised using the CHecklist for critical Appraisal and data extraction for systematic Reviews of prediction Modelling Studies (CHARMS). In addition, Grading of Recommendations Assessment, Development, and Evaluation (GRADE) was used as a guiding framework to assess certainty in the evidence for predicting outcomes across studies.ResultsThree thousand two hundred forty-nine articles were screened, of which ten articles were included in the review. All of the studies were conducted in neonatal intensive care units with sample sizes ranging from 22 to 9978, with a median of 163. Two articles reported model development, while eight reported external application of existing models to new populations. Meta-analysis was not possible due heterogeneity in the conduct and reporting of the identified studies. Discrimination as assessed by area under receiver operating characteristic curve was reported for in-hospital mortality, median 0.84 (range 0.75–0.96, three studies), early adverse outcome and late adverse outcome (0.78 and 0.59, respectively, one study).ConclusionExisting neonatal treatment intensity models show promise in predicting mortality and morbidity. There is however low certainty in the evidence on their performance in essential neonatal care in low resource settings as all studies had methodological limitations and were conducted in intensive care. The approach may however be developed further for low resource settings like Kenya because treatment data may be easier to obtain compared to measures of physiological status.Systematic review registrationPROSPERO CRD42016034205Electronic supplementary materialThe online version of this article (10.1186/s13643-017-0649-6) contains supplementary material, which is available to authorized users.

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Predictive Power of Serial Neonatal Therapeutic Intervention Scoring System Scores for Short-term Mortality in Very-low-birth-weight Infants

Abstract: The NTISS score at 48 hours seemed to be effective to predict mortality in preterm infants whose birth weight was less than 1500 g. In addition, gestational age played a more important role in predicting mortality than birth weight.

Cited by 14 publications

References 16 publications

Ventilator-Associated Pneumonia in Low Birth Weight Neonates at a Neonatal Intensive Care Unit: A Retrospective Observational Study

Ventilator-Associated Pneumonia in Low Birth Weight Neonates at a Neonatal Intensive Care Unit: A Retrospective Observational Study

Identificação da gravidade e do uso de intervenções em recém-nascidos com asfixia perinatal

A systematic review of neonatal treatment intensity scores and their potential application in low-resource setting hospitals for predicting mortality, morbidity and estimating resource use

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