Predictive Role of C-Reactive Protein/Albumin Ratio in Patients with Critical COVID-19 Patients

Kayhan, Sanem; Kozan, Hatice

doi:10.35440/hutfd.1001970

Cited by 3 publications

(1 citation statement)

References 24 publications

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“…Graciano et al (14) reported an approximately 70% decrease in admissions to intensive care units during the pandemic. COVID-19 primarily affects the upper respiratory tract, explaining the significant increase in the number of nose and throat cultures during the pandemic (15,16). The significant decrease in the number of ear cultures during the pandemic was a result of avoidance of ear infection risks (e.g., swimming pools).…”

Section: Discussionmentioning

confidence: 99%

The Effect of the Covid-19 Pandemic on the Number of Cultures Sent to the Microbiology Laboratory

Koparal

Akgün

2022

Harran Üniversitesi Tıp Fakültesi Dergisi

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Amaç: Bu çalışmanın amacı Covid-19 pandemisi sürecinde Türkiye’de bir Üniversite Hastanesi Tıbbı Mikrobiyoloji laboratuvarına gönderilen kulak, burun, boğaz, balgam, yara yeri kültürü numunelerindeki değişikliği pandemi öncesi dönem, pandeminin ilk tespit edildiği yıl ve takip eden süredeki sayısal değişikliğni saptayıp, bu yılları karşılaştırmaktır. Mataryel ve metod: Bu amaçla 2019,2020 ve 2021 yıllarında Mikrobiyoloji laboratuvarına gönderilen 2662 kültür değerlendirildi. Bu kültür numuleri çeşitlerine ve yıllara göre katagorize edilerek yıllar arasındaki değişim karşılaştırıldı. Bulgular: Bunların 1277’si (%48) kadın, 1385’i(%52) erkek hastaydı. Kadın hastaların yaş ortalamaları 58,06 erkek hastaların yaş ortalamaları 57,71 idi. Kültür sayıları 2019 yılı ile 2020 ve 2021 yılları arasunda karşılaştırıldığında istatistiksel açıdan anlamlı bulundu( p˂0.05). Balgam, yara yeri, burun, kulak, boğaz kültüründe de yıllar arasında istatiksel olarak anlamlı farklılık bulundu( p˂0.05). 2019 yılından sonra yara, balgam ve kulak kültürleri azalmış, pandemi yıllarında ise burun ve boğaz kültürlerinde artış olmuştur(2020,2021). Sonuç: Çalışmamız Covid-19 pandemisinin hastalıkların insidansında dolaylı olarak değişikliğe neden olduğunu laboratuvara gelen kültür sayılarındaki anlamlı değişiklik ile saptanmıştır.

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Section: Discussionmentioning

confidence: 99%

The Effect of the Covid-19 Pandemic on the Number of Cultures Sent to the Microbiology Laboratory

Koparal

Akgün

2022

Harran Üniversitesi Tıp Fakültesi Dergisi

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COVID-19 nedeniyle hastanede yatan hastaların CRP/albümin oranının prognoz üzerine etkisi

Şen

Tezcan

GOKCE

et al. 2022

Family Practice and Palliative Care

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Introduction: COVID-19 disease caused by the SARS-Cov-2 virus is characterized by clinical spectra of varying severity. Coagulopathy and inflammation are the most important factors associated with COVID-19 severity. The use of a biomarker of inflammation and coagulation factors has not yet been clarified. The present study aimed to examine the role of CRP/Albumin, an inflammation marker, in predicting the course of COVID-19 disease.Methods: The Demographic, laboratory, and prognosis of 457 patients who were hospitalized during the COVID-19 pandemic service between April and May 2020 were analyzed retrospectively. The relationship between the patients' CRP/Albumin ratio and disease severity, length of hospital stays, and prognosis were analyzed.Results: The rate of hospitalization in the intensive care unit was 10.5% (n=48), mechanical ventilation was 8.1% (n=37), and death was 1.3% (n=6). The CRP/albumin ratio was statistically higher in those with lung infiltration (p=0.005), those who were taken to the intensive care unit (p<0.001), and those who needed mechanical ventilation (p<0.001). A positive significant correlation was found between the length of hospital stay and the CRP/albumin ratio(r=0.412, p < 0.001).Conclusion: The CRP/Albumin ratio is thought to be an auxiliary marker for doctors in the early transfer of patients to the intensive care unit, the early detection of those in need of MV, and the determination of lung infiltration.Keywords: COVID-19, CRP/albumin ratio, prognosis

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Sistemik İnflamatuar İndeks, Nötrofil-Lenfosit Oranı ve Trombosit-Lenfosit Oranı Pediatrik Covid-19 Varyantlarını Saptayabilir mi?

ATAŞ,

KILINÇ,

YALÇIN

2023

Harran Üniversitesi Tıp Fakültesi Dergisi

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Background: Covid-19 has undergone many mutations over time. The most prominent variants have been the Alpha, Beta, Delta, Gamma, and finally, the Omicron variants. This study aims to determine the availability of neutrophil/lymphocyte rate (NLR), platelet/lymphocyte rate (PLR) and Systemic Inflammatory Index (SII), prog-nostic and diagnostic significance, in the differentiation of variants in pediatric Covid-19 patients. Materials and Methods: In this retrospective study, 141 pediatric patients who were found to be positive for Covid-19 in Harran University Medical Faculty Hospital between January 2021 and April 2022 were included. A control group was formed from 107 healthy children selected from among those who applied to the general pediatric outpatient clinic for routine health evaluations. Results: When the age distribution of the patients was examined, the median was 7.0 (0.1-18) years. When the variants were compared, there was a significant difference between lymphocyte values, while leukocyte, neu-trophil, C-reactive protein (CRP) and Mean Platelet Volume (MPV) did not change significantly. At the same time, there was a statistically significant difference between NLR, PLR and SII variants in Covid-19 positive patients (p<0.05); It was found that CRP, CRP/albumin rate (CAR), and MPV values did not change significantly between variants (p>0.05). It was observed that the NLR, PLR and SII delta variants increased significantly compared to the omicron variant (p<0.05). CRP and CAR were significantly increased in the severe clinical course compared to the asymptomatic group (p<0.05). Conclusions: In our study, it was seen that patients with delta variant had higher NLR, PLR and SII values compared to omicron variant when viewed from the point of view of Covid-19 variants. Therefore, we think that during the diagnosis of Covid-19 accompanied by these parameters, variant analysis can be performed, especially in terms of the delta variant, and it will shed light on the differential diagnosis, appropriate treatment, and measures to be taken by early and simple means.

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Predictive Role of C-Reactive Protein/Albumin Ratio in Patients with Critical COVID-19 Patients

Cited by 3 publications

References 24 publications

The Effect of the Covid-19 Pandemic on the Number of Cultures Sent to the Microbiology Laboratory

The Effect of the Covid-19 Pandemic on the Number of Cultures Sent to the Microbiology Laboratory

COVID-19 nedeniyle hastanede yatan hastaların CRP/albümin oranının prognoz üzerine etkisi

Sistemik İnflamatuar İndeks, Nötrofil-Lenfosit Oranı ve Trombosit-Lenfosit Oranı Pediatrik Covid-19 Varyantlarını Saptayabilir mi?

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