Predictive role of circulating endothelial-derived microparticles in cardiovascular diseases

Cellular Biomarkers of Endothelial Damage Associated With Adverse Prognosis in Acute Coronary Events

“…В проанализированной литературе особое вни-мание обращается на тот факт, что эндотелиаль-ные микрочастицы могут не только обеспечивать межклеточное взаимодействие, но и отражать выраженность повреждения эндотелиальных кле-ток, являться факторами повышенной коагуляции и воспаления, а также сами способствуют усугу-блению эндотелиальной дисфункции [18,19,20,21,22]. При динамическом исследовании клиренса циркулирующих микрочастиц во время сердечно-го стресс-теста было показано, что их повышение в ответ на стресс может быть нормальной физио-логической реакцией [23].…”

The number of red blood cell-derived microparticles in predicting periprocedural adverse effects in acute STsegment elevation myocardial infarction patients

“…MPs as derivate of cellular membrane are discussed powerful paracrine regulators of target cell functions [30][31][32]. Indeed, MPs possess a wide spectrum of biological effects on intercellular communication by transferring different molecules (autoantigens, cytokines, mRNA, iRNA, hormones, tissue coagulation factors, and surface receptors) able to modulate other cells affected growth of tissue, reparation, vasculogenesis, inflammation, apoptosis, infection, The number of red blood cell-derived microparticles in predicting periprocedural adverse effects in acute ST-segment elevation myocardial infarction patients Copyright: © 2017 Berezin and malignancy [33][34][35][36][37][38][39].…”

Biosensing of Circulating Apoptotic Endothelial Cell Micro particles: The Impact in Risk Stratification of Obesity

“…The proportion of these components as well as an entire secretome is under a tight control of autocrine/paracrine mechanisms and inflammatory factors (i.e. tumor necrosis factoralpha, interleukin-2, -6), which induces EMP formation in a timedependent manner [9,10,25]. Consequently, the final reply of the recipient cells, such as endothelial progenitor cells, is depends on epigenetic regulation of secretome secretion and primary trigger, which affects vesiculation of target cells [10].…”

“…MPs are originated from plasma membranes of various cells and secreted with specific process called "Vesiculation" [9]. As a derivate of cellular membrane MPs are discussed powerful autocrine and paracrine transducer of structure and functions of the target cells.…”