Predictive role of Selvester QRS score in patients undergoing transcatheter aortic valve replacement

Abstract

Introduction: Few data exist regarding the late clinical impact of the Selvester score prediction of myocardial fibrosis after transcatheter aortic valve replacement (TAVR). This study evaluated the predictive power of the Selvester score on survival in patients with aortic stenosis (AS) undergoing TAVR. METHODS AND RESULTS: Patients with severe AS who had preoperative electrocardiograms were included. Clinical follow-up was obtained retrospectively. The primary endpoint was all-cause mortality. Secondary endpoints were cardiovascular death and major adverse cardiac events (MACEs). Two-hundred twenty-eight patients were included (mean age, 81.5 ± 7.4 years; women, 58.3%). Deceased patients had a higher mean score (4.6 ± 3.2 vs. 1.4 ± 1.3; p < .001). At a mean follow-up of 36.2 ± 21.2 months, the Selvester score was independently associated with all-cause mortality (hazard ratio [HR], 1.65; 95% confidence interval [CI], 1.48-1.84; p < .001),

O Escore de Selvester QRS é um Preditor de Mortalidade na Insuficiência Cardíaca com Fração de Ejeção Preservada

“…This resulted from a 2-year follow-up of 289 patients after MI with ST elevation compared to patients without it. In the study by Bignoti et al, 13 228 patients who underwent transcatheter valve replacement for aortic valve stenosis were followed up for 36.2 ± 21.2 months and showed a 1.59-fold higher cardiovascular mortality rate in patients with high S-QRS scores. 13 In the study by Hirawi et al, 12 a 1.32-fold higher rate of fatal cardiac events was observed in patients with high S-QRS scores after a mean follow-up of 4.5 ± 3.2 years in 91 patients with non-ischemic cardiomyopathy.…”

“…In the study by Bignoti et al, 13 228 patients who underwent transcatheter valve replacement for aortic valve stenosis were followed up for 36.2 ± 21.2 months and showed a 1.59-fold higher cardiovascular mortality rate in patients with high S-QRS scores. 13 In the study by Hirawi et al, 12 a 1.32-fold higher rate of fatal cardiac events was observed in patients with high S-QRS scores after a mean follow-up of 4.5 ± 3.2 years in 91 patients with non-ischemic cardiomyopathy. In addition, a high correlation with the S-QRS score of collagen fraction measured by endomyocardial biopsy was found.…”

“…[30][31][32] O estudo prospectivo de Liu et al, 33 mostraram que a mortalidade cardiovascular aumentou 1,46 vezes em pacientes com escores S-QRS elevados. Isso resultou de um acompanhamento de 2 anos de 289 pacientes após infarto do miocárdio com elevação do segmento ST em comparação com pacientes sem elevação do segmento ST. No estudo de Bignoto et al, 13 228 pacientes submetidos à substituição valvar transcateter para estenose valvar aórtica foram acompanhados por 36,2 ± 21,2 meses e apresentaram uma taxa de mortalidade cardiovascular 1,59 vezes maior em pacientes com altos escores de S-QRS. 13 No estudo de Hirawi et al, 12 uma taxa 1,32 vezes maior de eventos cardíacos fatais foi observada em pacientes com altos escores S-QRS após seguimento médio de 4,5 ± 3,2 anos em 91 pacientes com cardiomiopatia não isquêmica.…”

“…9 Em muitos estudos clínicos, um escore S-QRS alto demonstrou fornecer informações sobre O diagrama mostra a seleção dos grupos de 10,11 Seu valor prognóstico foi relatado em muitos estudos cardiovasculares doenças, como cardiomiopatia não isquêmica, estenose aórtica e cardiomiopatia hipertrófica. [12][13][14] No entanto, não há informações sobre sua associação com ICFEp.…”