The purpose of the study was to determine which NANDA nursing diagnosis are made and which related NIC nursing interventions are carried out most frequently by clinical nursing experts. Methods: The Likert Scale and Fehring´s Diagnostic Content Validity Model (DCV model) were used for the research. Sample: The total number of all participants of the validation research, i.e. academic nurses/experts, and clinical nurses/experts (nc=848) from 2 countries – SR and CR, consisted of 4 subsamples. A total of 69 items – activities of two interventions for NIC nursing diagnosis: Risk for Infection 00004 were evaluated. Results: We found out that the total set of experts rated all activities/practices of Intervention I and II as significant. Conclusion: The results of the international study provide valid findings for the development of nursing care and curriculum for future professionals.